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      Monopolar versus bipolar transurethral resection of lateral wall-located bladder cancer under obturator nerve block: a single center prospective randomized study

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          ABSTRACT

          Introduction:

          The aim of the present prospective-randomized study was to compare perioperative outcomes and complications of bipolar and monopolar TURBT for lateral wall-located non-muscle invasive bladder cancers (NMIBC) under obturator nerve block (ONB).

          Patients and Methods:

          80 patients who underwent TURBT for lateral wall-located primary bladder tumors under ONB from March, 2016 to November, 2019 were included in the present study. The patients were randomized equally into two groups; monopolar TUR (M-TURBT) and bipolar TUR (B-TURBT). The primary and secondary outcomes were safety (obturator jerk and bladder perforation) and efficacy (complete tumor resection and sampling of the deep muscle tissue).

          Results:

          Obturator jerk was detected in 2 patients (5%) in M-TURBT while obturator jerk was not observed during B-TURBT (p=0.494). Bladder perforation was not observed in both groups. All of the patients underwent complete tumor resection. There was no significant difference in muscle tissue sampling (67.5% vs. 72.5%, p=0.626) and thermal tissue damage rates (12.5% vs. 25%, p=0.201). The majority of complications were low-grade and the differences in Clavien grade 1-3 complications between groups were not statistically significant.

          Conclusion:

          In the treatment of lateral-wall located NMIBCs, either M-TURBT or B-TURBT can be safely and effectively performed by combining spinal anesthesia with ONB. Even so, it should be taken into consideration that low-grade postoperative hemorrhagic complications may occur in patients who undergo M-TURBT.

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          Most cited references30

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          European Association of Urology Guidelines on Non-muscle-invasive Bladder Cancer (TaT1 and Carcinoma In Situ) - 2019 Update

          This overview presents the updated European Association of Urology (EAU) guidelines for non-muscle-invasive bladder cancer (NMIBC), TaT1, and carcinoma in situ (CIS).
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            Epidemiology of Bladder Cancer: A Systematic Review and Contemporary Update of Risk Factors in 2018

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              Epidemiology of Bladder Cancer

              Based on the latest GLOBOCAN data, bladder cancer accounts for 3% of global cancer diagnoses and is especially prevalent in the developed world. In the United States, bladder cancer is the sixth most incident neoplasm. A total of 90% of bladder cancer diagnoses are made in those 55 years of age and older, and the disease is four times more common in men than women. While the average 5-year survival in the US is 77%, the 5-year survival for those with metastatic disease is a measly 5%. The strongest risk factor for bladder cancer is tobacco smoking, which accounts for 50–65% of all cases. Occupational or environmental toxins likewise greatly contribute to disease burden (accounting for an estimated 20% of all cases), though the precise proportion can be obscured by the fact bladder cancer develops decades after exposure, even if the exposure only lasted several years. Schistosomiasis infection is the common cause of bladder cancer in regions of Africa and the Middle East and is considered the second most onerous tropical pathogen after malaria. With 81% of cases attributable to known risk factors (and only 7% to heritable mutations), bladder cancer is a prime candidate for prevention strategies. Smoking cessation, workplace safety practices, weight loss, exercise and schistosomiasis prevention (via water disinfection and mass drug administration) have all been shown to significantly decrease the risk of bladder cancer, which poses a growing burden around the world.
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                Author and article information

                Journal
                Int Braz J Urol
                Int Braz J Urol
                ibju
                International Brazilian Journal of Urology : official journal of the Brazilian Society of Urology
                Sociedade Brasileira de Urologia
                1677-5538
                1677-6119
                20 December 2020
                May-Jun 2021
                : 47
                : 3
                : 584-593
                Affiliations
                [1 ] orgnameUniversity of Health Sciences orgdiv1Bozyaka Training and Research Hospital Izmir Turkey originalUniversity of Health Sciences, Bozyaka Training and Research Hospital, Izmir, Turkey
                Author notes
                Correspondence address: Deniz Bolat, MD, FEBU, Department of Urology, University of Health Sciences, Izmir Bozyaka Training and Research Hospital, Saim Cikrikci Street No:59. Karabaglar, Izmir, Turkey. Telephone: + 90 5056383010 E-mail: drbolat@ 123456hotmail.com

                CONFLICT OF INTEREST

                None declared.

                Author information
                https://orcid.org/0000-0001-7338-8737
                Article
                S1677-5538.IBJU.2020.0568
                10.1590/S1677-5538.IBJU.2020.0568
                7993959
                33621007
                4fb482d0-f6d0-4cc0-b61a-12a788ab3ada

                This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 30 June 2020
                : 25 August 2020
                Page count
                Figures: 2, Tables: 2, Equations: 0, References: 28, Pages: 10
                Categories
                Original Article

                urinary bladder neoplasms,transurethral resection of prostate,prostatectomy

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