Impact of diet and nutraceutical supplementation on inflammation in elderly people. Results from the RISTOMED study, an open-label randomized control trial.

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Abstract

Eating habits may influence the life span and the quality of ageing process by modulating inflammation. The RISTOMED project was developed to provide a personalized and balanced diet, enriched with or without nutraceutical compounds, to decrease and prevent inflammageing, oxidative stress and gut microbiota alteration in healthy elderly people. This paper focused on the effect on inflammation and metabolism markers after 56 days of RISTOMED diet alone or supplementation with three nutraceutical compounds.

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Journal

Journal ID (iso-abbrev): Clin Nutr

Title: Clinical nutrition (Edinburgh, Scotland)

ISSN (Electronic): 1532-1983

ISSN (Print): 0261-5614

Publication date (Electronic): Aug 2016

Volume: 35

Issue: 4

Affiliations

[1 ] Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Via San Giacomo 12, 40126 Bologna, Italy.

[2 ] Hematology Laboratory, University Hospital CHU, 9 Quai Moncousu, 44000 Nantes, France.

[3 ] Biostatistical Center INRCA, Via S. Margherita 5, 60100 Ancona, Italy.

[4 ] Experimental Medicine Department, Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy.

[5 ] Institute for Organic Synthesis and Photoreactivity, National Research Council of Italy, CNR, (ISOF), Via P. Gobetti 101, 40129 Bologna, Italy.

[6 ] Department of Chemistry, University Mohammed V-Agdal, Rabat, Morocco.

[7 ] Department Gastroenterology and Hepatology, Charité-Universitätsmedizin Berlin, CCM, Charitéplatz 1, 10117 Berlin, Germany.

[8 ] Medical University of Innsbruck, Innrain 52, 6020 Innsbruck, Austria.

[9 ] CHU Bordeaux, Clinical Gerontology, France; CNRS, RMSB, UMR 5536, France; University Bordeaux, RMSB, UMR 5536, Bordeaux, France.

[10 ] R&D, VoxNet CEO, Via Giovanni Paisiello 32, 00198 Rome, Italy.

[11 ] Department of Pharmacy and Biotechnology, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.

[12 ] Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Via San Giacomo 12, 40126 Bologna, Italy; IRCCS, Institute of Neurological Sciences, Via Altura 3, 40139 Bologna, Italy; National Research Council of Italy, CNR, Institute for Organic Synthesis and Photoreactivity (ISOF), Via P. Gobetti 101, 40129 Bologna, Italy.

[13 ] Biopark Campus Cancer, 1 mail du Pr Georges Mathé, 94807 Villejuif, France. Electronic address: endocell@wanadoo.fr.

Article

Publisher Item ID: S0261-5614(15)00188-0

DOI: 10.1016/j.clnu.2015.06.010

PubMed ID: 26249791

SO-VID: 50b0ecda-2ae9-4c74-8881-3cd58c12bd1a

History

Keywords: Ageing,Diet,Inflammation,Nutraceutics,Probiotics,d-Limonene

Data availability:

Keywords: Ageing, Diet, Inflammation, Nutraceutics, Probiotics, d-Limonene

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