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Paraoxonase 1 (PON1) 55 polymorphism, lipid profiles and psoriasis.
M Asefi
1 ,
A Vaisi-Raygani ,
F Bahrehmand ,
A Kiani ,
Z Rahimi ,
H Nomani ,
A Ebrahimi ,
H Tavilani ,
T Pourmotabbed
Dec 2012
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Abstract
Paraoxonase 1 (PON1) is a serum high-density lipoprotein-bound enzyme with antioxidant function. It hydrolyses lipid peroxides, protecting low-density lipoproteins from oxidative modifications. Patients with psoriasis are at greater risk of oxidative stress, which is associated with abnormal plasma lipid metabolism.