Nanoemulsion: an advanced mode of drug delivery system

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

An advanced mode of drug delivery system has been developed to overcome the major drawbacks associated with conventional drug delivery systems. This review gives a detailed idea about a nanoemulsion system. Nanoemulsions are nano-sized emulsions, which are manufactured for improving the delivery of active pharmaceutical ingredients. These are the thermodynamically stable isotropic system in which two immiscible liquids are mixed to form a single phase by means of an emulsifying agent, i.e., surfactant and co-surfactant. The droplet size of nanoemulsion falls typically in the range 20–200 nm. The main difference between emulsion and nanoemulsion lies in the size and shape of particles dispersed in the continuous phase. In this review, the attention is focused to give a basic idea about its formulation, method of preparation, characterization techniques, evaluation parameters, and various applications of nanoemulsion.

Related collections

Most cited references 22

Record: found
Abstract: not found
Article: not found

Nano-emulsions

C. Solans, P Izquierdo, J Nolla … (2005)

0 comments Cited 211 times – based on 0 reviews      Review now

Bookmark

Record: found
Abstract: found
Article: not found

Design and production of nanoparticles formulated from nano-emulsion templates-a review.

Nicolas Anton, Jean-Pierre Benoit, Patrick Saulnier (2008)

A considerable number of nanoparticle formulation methods are based on nano-emulsion templates, which in turn are generated in various ways. It must therefore be taken into account that active principles and drugs encapsulated in nanoparticles can potentially be affected by these nano-emulsion formulation processes. Such potential differences may include drug sensitivity to temperature, high-shear devices, or even contact with organic solvents. Likewise, nano-emulsion formulation processes must be chosen in function of the selected therapeutic goals of the nano-carrier suspension and its administration route. This requires the nanoparticle formulation processes (and thus the nano-emulsion formation methods) to be more adapted to the nature of the encapsulated drugs, as well as to the chosen route of administration. Offering a comprehensive review, this paper proposes a link between nano-emulsion formulation methods and nanoparticle generation, while at the same time bearing in mind the above-mentioned parameters for active molecule encapsulation. The first part will deal with the nano-emulsion template through the different formulation methods, i.e. high energy methods on the one hand, and low-energy ones (essentially spontaneous emulsification and the phase inversion temperature (PIT) method) on the other. This will be followed by a review of the different families of nanoparticles (i.e. polymeric or lipid nanospheres and nanocapsules) highlighting the links (or potential links) between these nanoparticles and the different nano-emulsion formulation methods upon which they are based.

0 comments Cited 205 times – based on 0 reviews      Review now

Bookmark

Record: found
Abstract: not found
Article: not found

Miniemulsion polymerization

José Asua (2002)

0 comments Cited 131 times – based on 0 reviews      Review now

Bookmark

All references

Author and article information

Contributors

Manjit Jaiswal: manjitj2@gmail.com

Journal

Journal ID (nlm-ta): 3 Biotech

Journal ID (iso-abbrev): 3 Biotech

Title: 3 Biotech

Publisher: Springer Berlin Heidelberg (Berlin/Heidelberg )

ISSN (Print): 2190-572X

ISSN (Electronic): 2190-5738

Publication date (Electronic): 8 April 2014

Publication date PMC-release: 8 April 2014

Publication date (Print): April 2015

Volume: 5

Issue: 2

Pages: 123-127

Affiliations

Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, G. B. Nagar, Uttar Pradesh India

Article

Publisher ID: 214

DOI: 10.1007/s13205-014-0214-0

PMC ID: 4362737

PubMed ID: 28324579

SO-VID: 54980c2f-a71d-44ab-a272-71d7e440dce8

License:

Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.