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      Osteonecrosis repair with bone marrow cell therapies: state of the clinical art.

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          Abstract

          Hip osteonecrosis is a pathological condition resulting from cellular impairment due to reduction in osteoblast activity and local mesenchymal stem cell populations. Cell-based therapies might aid in overcoming these deficiencies by providing stem cells and other progenitor cells to potentially improve the local cellular environment in the affected hip.

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          Author and article information

          Journal
          Bone
          Bone
          1873-2763
          1873-2763
          Jan 2015
          : 70
          Affiliations
          [1 ] Orthopaedic Surgery, University Paris East, Hôpital Henri Mondor, 94010 Creteil, France. Electronic address: philippe.hernigou@wanadoo.fr.
          [2 ] University Paris East, Hôpital Henri Mondor, 94010 Creteil, France.
          [3 ] Orthopaedic Surgery, University Paris East, Hôpital Henri Mondor, 94010 Creteil, France.
          [4 ] EFS Cell Therapy Facility, University Paris East, Hôpital Henri Mondor, 94010 Creteil, France.
          Article
          S8756-3282(14)00257-9
          10.1016/j.bone.2014.04.034
          25016964
          56b6c7ad-5b68-4835-a91e-dd7bdf01c524
          Copyright © 2014 Elsevier Inc. All rights reserved.
          History

          Bone marrow,Cytotherapy,Hip osteonecrosis,Mesenchymal stem cells,Osteonecrosis

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