+1 Recommend
1 collections
      • Record: found
      • Abstract: found
      • Article: found

      Determination of the Anaerobic Threshold in the Evaluation of Functional Status before and following Valve Replacement for Aortic Regurgitation

      , ,


      S. Karger AG

      Echocardiography, Exercise testing, Aortic valve replacement

      Read this article at

          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.


          The effect of aortic valve replacement on exercise capacity was evaluated in 28 patients with aortic regurgitation using repeat determinations of peak oxygen uptake (VO<sub>2</sub>) and the anaerobic threshold (AT), based on a nonlinear increase in the plot of pulmonary ventilation versus VO<sub>2</sub>. Although the AT was on average 68% of peak VO<sub>2</sub> before and 1 year after surgery, the test-to-test correlation coefficient was 0.92 for the AT but only 0.68 for peak VO<sub>2</sub> postoperatively. 11 patients (39 %) improved in AT, usually within the first 6 months. The preoperative echocardiographic left ventricular end-diastolic dimension and its postoperative change correlated with that in the AT (r = 0.64 and -0.60, p < 0.001) but not with that in peak VO<sub>2</sub>. The patients likely to improve had a lower AT (p < 0.05) preoperatively, however. Thus repeat determinations of AT using respiratory measurements give additional data on changes in functional status. Sequential exercise testing does not require the patient to be exercised much past his AT.

          Related collections

          Author and article information

          S. Karger AG
          11 November 2008
          : 72
          : 4
          : 165-173
          Division of Cardiology, Department of Internal Medicine, University Central Hospital, Oulu, Finland
          173870 Cardiology 1985;72:165–173
          © 1985 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 9
          Original Paper


          Comment on this article