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      Effects of herbal yogurt with fish collagen on bioactive peptides with angiotensin-I converting enzyme inhibitory activity

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          Abstract

          Abstract Illicium verum (IV; dried fruit), Psidium guajava (PG; dried leaves), and Curcuma longa (CL; dried rhizome) water extract and/or fish collagen were added into yogurt to determine their effects on acidification and the proteolysis of milk up to 21 days of storage at 4°C. The angiotensin-I converting enzyme (ACE) test was conducted to analyze the inhibitory activity of bioactive peptides produced during proteolytic activity on the ACE enzyme. The addition of fish collagen in PG- yogurt significantly decreased pH compared to control on day 7 of storage. The presence of IV, PG, and CL enhanced (p<0.05) OPA peptide amount during 7 & 14 days of storage. The highest ACE inhibitory activity was shown on day 7 for all herbal yogurt. Herbal yogurt either in the presence or absence of fish collagen may improve the manufacture and formulation of yogurt with anti-ACE activity.

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          Spectrophotometric Assay Using o-Phthaldialdehyde for Determination of Proteolysis in Milk and Isolated Milk Proteins

          George Catignani, Frank Church, David Porter … (1983)
          Article 0 comments Cited 144 times – based on 0 reviews     Review now
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            Phytochemicals for human disease: An update on plant-derived compounds antibacterial activity.

            Ramona Barbieri, Erika Coppo, Anna Marchese … (2017)
            In recent years, many studies have shown that phytochemicals exert their antibacterial activity through different mechanisms of action, such as damage to the bacterial membrane and suppression of virulence factors, including inhibition of the activity of enzymes and toxins, and bacterial biofilm formation. In this review, we summarise data from the available literature regarding the antibacterial effects of the main phytochemicals belonging to different chemical classes, alkaloids, sulfur-containing phytochemicals, terpenoids, and polyphenols. Some phytochemicals, besides having direct antimicrobial activity, showed an in vitro synergistic effect when tested in combination with conventional antibiotics, modifying antibiotic resistance. Review of the literature showed that phytochemicals represent a possible source of effective, cheap and safe antimicrobial agents, though much work must still be carried out, especially in in vivo conditions to ensure the selection of effective antimicrobial substances with low side and adverse effects.
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              Role of the Renin-Angiotensin-Aldosterone System beyond Blood Pressure Regulation: Molecular and Cellular Mechanisms Involved in End-Organ Damage during Arterial Hypertension

              Natalia Muñoz-Durango, Cristóbal Fuentes, Andrés E. Castillo … (2016)
              Arterial hypertension is a common condition worldwide and an important predictor of several complicated diseases. Arterial hypertension can be triggered by many factors, including physiological, genetic, and lifestyle causes. Specifically, molecules of the renin-angiotensin-aldosterone system not only play important roles in the control of blood pressure, but they are also associated with the genesis of arterial hypertension, thus constituting a need for pharmacological interventions. Chronic high pressure generates mechanical damage along the vascular system, heart, and kidneys, which are the principal organs affected in this condition. In addition to mechanical stress, hypertension-induced oxidative stress, chronic inflammation, and the activation of reparative mechanisms lead to end-organ damage, mainly due to fibrosis. Clinical trials have demonstrated that renin-angiotensin-aldosterone system intervention in hypertensive patients lowers morbidity/mortality and inflammatory marker levels as compared to placebo patients, evidencing that this system controls more than blood pressure. This review emphasizes the detrimental effects that a renin-angiotensin-aldosterone system (RAAS) imbalance has on health considerations above and beyond high blood pressure, such as fibrotic end-organ damage.
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                Author and article information

                Journal
                Journal ID (publisher-id): cta
                Title: Food Science and Technology
                Abbreviated Title: Food Sci. Technol
                Publisher: Sociedade Brasileira de Ciência e Tecnologia de Alimentos (Campinas, SP, Brazil )
                ISSN (Print): 0101-2061
                ISSN (Electronic): 1678-457X
                Publication date (Print and electronic): 2020
                Affiliations
                [01] Jeddah orgnameKing Abdulaziz University orgdiv1Faculty of Science orgdiv2Department of Biological Sciences Saudi Arabia
                [02] Kuala Lumpur Kuala Lumpur orgnameUniversity of Malaya orgdiv1Faculty of Science orgdiv2Institute of Biological Sciences Malaysia
                Article
                Other ID: 24214 Publisher ID: S0101-20612020005024214 Publisher ID: S0101-2061(20)00000024214
                DOI: 10.1590/fst.24020
                SO-VID: 585ee2a3-5d39-46b2-9d96-444823334c1d
                License:

                This work is licensed under a Creative Commons Attribution 4.0 International License.

                History
                Date received : 01 June 2020
                Date accepted : 17 August 2020
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 41, Pages: 0
                Product

                SciELO Brazil


                Keywords: ACE inhibitory activity,fish collagen,proteolysis,herbal water extract,yogurt
                Data availability:
                Keywords: ACE inhibitory activity, fish collagen, proteolysis, herbal water extract, yogurt

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