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      Hipercolesterolemia Y factores de riesgo asociados, ambulatorio urbano II: Dr. Leonardo Ruiz Pineda II, San Agustín del Sur, Caracas, Venezuela, año 2002

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          La hipercolesterolemia es uno de los principales factores de riesgo cardiovascular modificables el presente estudio se realizó en el ambulatorio leonardo ruiz pineda ii, para determinar los factores de riesgo asociados a hipercolesterolemia, de los pacientes de ambos sexos, entre las edades de 20 a 85 años, que acuden a este centro. la metodología utilizada fue una investigación descriptiva mediante corte transversal, obteniendo la muestra a través de jornadas procurando una buena representatividad y llenando la encuesta de factores de riesgo cardiovascular de la sociedad venezolana de cardiología. se tomó peso, talla, presión arterial, glicemia y colesterol. se encontró una asociación directa y significativa entre la prevalencia de hipercolesterolemia y las de: hipertensión arterial, sobrepeso u obesidad y diabetes, de nivel bastante alto para las dos primeras y moderado para diabetes. en el grupo de menores de 30 años hubo mayor prevalencia de hipertensión, diabetes y sobrepeso u obesidad en el sexo masculino que en el femenino. en el grupo de mayores de 30 años, hubo mayor prevalencia de hipertensión arterial y sobrepeso u obesidad en el sexo femenino mientras la hipercolesterolemia fue mayor en el sexo masculino. para ambos sexos se aprecia un incremento notable de la presencia de todos los factores de riesgo en el grupo etario de más de 30. las frecuencias para los factores de riesgo difieren significativamente de las halladas en consulta así como la odd ratio para obesidad e hipercolesterolemia.

          Translated abstract

          The Hypercholesterolemia is one of the main modifiable factors of cardiovascular risk The present study was made in the ambulatory Leonardo Ruiz Pineda II, to determine the associated factors of risk to Hypercholesterolemia, of the patients of both sexes, between the ages of 20 to 85 years, that go to this health’s centre. The used Methodology was a descriptive investigation by means of cross section, obtaining the sample through days trying a good representative ness and filling the survey of factors of cardiovascular risk of the Venezuelan Society of Cardiology. Weight was taken, carves, arterial pressure, glycaemia and cholesterol. One was a direct and significant association between the prevalence of Hypercholesterolemia and those of: Arterial hypertension, Overweight or obesity and Diabetes, of quite high level for two first and the moderate one for Diabetes. In the group of minors of 30 years there was greater prevalence of Hypertension, Diabetes and Overweight or obesity in the masculine sex that in the feminine one. In the group of greater of 30 years, there was greater prevalence of arterial Hypertension and Overweight or obesity in feminine sex while the Hypercholesterolemia was greater in masculine sex. For both sexes a remarkable increase of the presence of all the factors of risk in the etario group of more is appraised than 30. The frequencies for the risk factors differ significantly from found in consultation as well as odd ratio for hypercholesterolemia to obesity.

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          Most cited references 31

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          Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III).

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            The sixth report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure.

            Racial and ethnic minority populations are growing segments of our society. The prevalence of hypertension in these populations differs across groups, and control rates are not as good as in the general population. Clinicians should be aware of these management challenges, taking social and cultural factors into account. Guidelines are provided for management of children and women with hypertension. In older persons, diuretics are preferred and long-acting dihydropyridine calcium antagonists may be considered. Specific therapy for patients with LVH, coronary artery disease, and heart failure are outlined. Patients with renal insufficiency with greater than 1 g/d of proteinuria should be treated to a therapy blood pressure goal of 125/75 mm Hg; those with less proteinuria should be treated to a blood pressure goal of 130/85 mm Hg. ACE inhibitors have additional renoprotective effects over other antihypertensive agents. Patients with diabetes should be treated to a therapy blood pressure goal of below 130/85 mm Hg. Hypertension may coexist with various other conditions and may be induced by various pressor agents.
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              Mortality in relation to smoking: 40 years' observations on male British doctors.

               R. Peto,  R Doll,  L. Gray (1994)
              To assess the hazards associated with long term use of tobacco. Prospective study of mortality in relation to smoking habits assessed in 1951 and again from time to time thereafter, with causes sought of deaths over 40 years (to 1991). Continuation of a study that was last reported after 20 years' follow up (1951-71). 34,439 British male doctors who replied to a postal questionnaire in 1951, of whom 10,000 had died during the first 20 years and another 10,000 have died during the second 20 years. Excess mortality associated with smoking was about twice as extreme during the second half of the study as it had been during the first half. The death rate ratios during 1971-91 (comparing continuing cigarette smokers with life-long non-smokers) were approximately threefold at ages 45-64 and twofold at ages 65-84. The excess mortality was chiefly from diseases that can be caused by smoking. Positive associations with smoking were confirmed for death from cancers of the mouth, oesophagus, pharynx, larynx, lung, pancreas, and bladder; from chronic obstructive pulmonary disease and other respiratory diseases; from vascular diseases; from peptic ulcer; and (perhaps because of confounding by personality and alcohol use) from cirrhosis, suicide, and poisoning. A negative association was confirmed with death from Parkinson's disease. Those who stopped smoking before middle age subsequently avoided almost all of the excess risk that they would otherwise have suffered, but even those who stopped smoking in middle age were subsequently at substantially less risk than those who continued to smoke. Results from the first 20 years of this study, and of other studies at that time, substantially underestimated the hazards of long term use of tobacco. It now seems that about half of all regular cigarette smokers will eventually be killed by their habit.

                Author and article information

                [1 ] Hospital José Gregorio Hernández
                [2 ] Universidad Central de Venezuela
                [3 ] Alcaldía Metropolitano del Distrito Capital
                Role: ND
                Role: ND
                Role: ND
                Revista de la Facultad de Medicina
                Universidad Central de Venezuela. Facultad de Medicina. Comisión de Publicaciones de la Facultad de Medicina (Caracas )
                : 28
                : 1
                : 63-74


                Product Information: SciELO Venezuela


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