C677T and A1298C methylenetetrahydrofolate reductase polymorphisms and breast cancer susceptibility among Latinos: a meta-analysis.

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Abstract

Previous meta-analyses have shown an ethnic dependency of the C677T and the A1298C methylenetetrahydrofolate reductase (MTHFR) polymorphisms, with no focus on the Latino population. For Latinos, many studies have examined these polymorphisms and breast cancer susceptibility, yielding no concise result. Therefore, we undertook this meta-analysis to determine the effect these polymorphisms have on breast cancer risk for Latinos.

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Author and article information

Journal

Journal ID (iso-abbrev): Breast Cancer

Title: Breast cancer (Tokyo, Japan)

Publisher: Springer Science and Business Media LLC

ISSN (Electronic): 1880-4233

ISSN (Print): 1340-6868

Publication date (Electronic): Sep 2019

Volume: 26

Issue: 5

Affiliations

[1 ] Departamento de Genética, Facultad de Medicina, Benemérita Universidad Autónoma de Puebla, 13 Sur 2901 Col. Volcanes, C.P. 72420, Puebla, Pue, Mexico.

[2 ] Laboratorio de Investigación en Fisiopatología de Enfermedades Crónicas, Centro de Investigación Biomédica de Oriente, IMSS, Km 4.5 Carretera Federal Atlixco-Metepec, C.P. 42730, Atlixco, Puebla, Mexico.

[3 ] Facultad de Medicina, Benemérita Universidad Autónoma de Puebla, 13 Sur 2901 Col. Volcanes, C.P. 72420, Puebla, Pue, Mexico.

[4 ] Departamento de Genética, Facultad de Medicina, Benemérita Universidad Autónoma de Puebla, 13 Sur 2901 Col. Volcanes, C.P. 72420, Puebla, Pue, Mexico. elba.gonzalezmejia@gmail.com.

Article

Publisher Item ID: 10.1007/s12282-019-00961-8

DOI: 10.1007/s12282-019-00961-8

PubMed ID: 30877449

SO-VID: 5a5bcff8-8cd9-41b0-8c2f-f859fd794c68

History

Keywords: MTHFR,Latin America,Mutation,Carcinogenesis

Data availability:

Keywords: MTHFR, Latin America, Mutation, Carcinogenesis

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