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      The presence of P2RX7 single nuclear polymorphism is associated with a gain of function in P2X7 receptor and inflammasome activation in SLE complicated with pericarditis.

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          Abstract

          A case control study was conducted to evaluate the possible influence of P2RX7 single nuclear polymorphism and P2X7 receptor activity in the susceptibility of SLE with pericarditis in Chinese Han population.

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          Author and article information

          Journal
          Clin Exp Rheumatol
          Clinical and experimental rheumatology
          0392-856X
          0392-856X
          August 4 2019
          : 38
          : 3
          Affiliations
          [1 ] Division of Rheumatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
          [2 ] Division of Gastroenterology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
          [3 ] Division of Rheumatology, Wuhan PuAi Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
          [4 ] Division of Endocrinology and Rheumatology, HuangPi People's Hospital, The Third Affiliated Hospital of Jianghan University, Wuhan, China.
          [5 ] State Key Laboratory of Natural Medicines, Department of Physiology, China Pharmaceutical University, Nanjing, China.
          [6 ] Division of Rheumatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. yuyikai@163.com.
          Article
          13579
          31376246
          5b13d94a-35d9-402f-8cd7-69c304ecb4c5
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