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      Effect of Atrial and Ventricular Activation Interval on Hemodynamics during Atrioventricular and Ventriculoatrial Pacing: Determination from Pressure-Volume Loops in Dogs

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          Abstract

          To determine the effect of relative timing of atrial and ventricular activation on hemodynamic indices, we evaluated pressure-volume loops during pacing at 160 beats/min with various atrioventricular intervals in dogs. End-systolic pressure, end-diastolic volume, and stroke volume were reduced during pacing at atrioventricular intervals of 0 ms, compared with 80 ms. These changes were more significant during pacing at atrioventricular intervals of-50 and -100 ms than at 0 ms. During tachycardia, the abnormal timing of atrial contraction leads to unfavorable hemodynamic change and the degree of the changes are determined by the ventriculoatrial activation interval.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          0008-6312
          1421-9751
          1995
          1995
          18 November 2008
          : 86
          : 1
          : 28-33
          Affiliations
          Second Department of Internal Medicine, Kansai Medical University, Osaka, Japan
          Article
          176827 Cardiology 1995;86:28–33
          10.1159/000176827
          7728785
          © 1995 S. Karger AG, Basel

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          Page count
          Pages: 6
          Categories
          Arrhythmias, Electrophysiology and Electrocardiography

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