Endogenously produced adenosine regulates articular cartilage matrix homeostasis: enzymatic depletion of adenosine stimulates matrix degradation.

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Enhanced extracellular levels of adenosine have been shown to inhibit experimentally induced cartilage degradation. The objective of this study was to investigate the role of adenosine and A(2)adenosine receptors in regulating cartilage homeostasis in the absence of inflammatory stimuli.

Related collections

Author and article information

Journal

Journal ID (iso-abbrev): Osteoarthr. Cartil.

Title: Osteoarthritis and cartilage

Publisher: Elsevier BV

ISSN: 1063-4584

ISSN (Print): 1063-4584

Publication date (Electronic): May 2004

Volume: 12

Issue: 5

Affiliations

[1 ] Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California-Davis, Davis, CA 95616, USA.

Article

Publisher Item ID: S1063458404000056

DOI: 10.1016/j.joca.2004.01.002

PubMed ID: 15094133

SO-VID: 5c3b86aa-8c63-4a8f-be49-1dee4b19bf98

History

Data availability:

Comments

Comment on this article

scite_

Cited by 14

See all cited by