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      Survival of 11,390 Continuum cups in primary total hip arthroplasty based on data from the Finnish Arthroplasty Register

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          Abstract

          Background and purpose — The use of trabecular metal (TM) cups for primary total hip arthroplasty (THA) is increasing. Some recent data suggest that the use of TM in primary THA might be associated with an increased risk of revision. We compared implant survival of Continuum acetabular cups with other commonly used uncemented cups.

          Patients and methods — Data on 11,390 primary THAs with the Continuum cup and 30,372 THAs with other uncemented cups (reference group) were collected from the Finnish Arthroplasty Register. Kaplan–Meier survival estimates were calculated; the endpoint was revision for any reason, for infection, or for dislocation. Revision risks were assessed with adjusted Cox multiple regression models. A subgroup analysis on the use of neutral or elevated liners in the Continuum group was made.

          Results — The 7-year survivorship of the Continuum group was 94.6% (95% CI 94.0–95.2) versus 95.6% (CI 95.3–95.8) in the reference group for revision for any reason. The risk for revision was higher in the Continuum group than in the reference group both for revision for any reason (HR 1.3 [CI 1.2–1.5)]) and for revision for dislocation (HR 1.9 [CI 1.5–2.3]). There was no difference in the rates of revision because of infection (HR 0.99 [CI 0.78–1.3]). Use of a neutral liner increased the risk for revision due to dislocation in comparison with the use of an elevated rim liner in the Continuum group (HR 1.7 [CI 1.2–2.5]).

          Interpretation — THA with Continuum cups is associated with an increased risk of revision compared with other uncemented cups, mainly due to revisions because of dislocation. Our results support the use of an elevated liner when Continuum cups are used for primary THA.

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          Increasing risk of prosthetic joint infection after total hip arthroplasty

          Background and purpose The risk of revision due to infection after primary total hip arthroplasty (THA) has been reported to be increasing in Norway. We investigated whether this increase is a common feature in the Nordic countries (Denmark, Finland, Norway, and Sweden). Materials and methods The study was based on the Nordic Arthroplasty Register Association (NARA) dataset. 432,168 primary THAs from 1995 to 2009 were included (Denmark: 83,853, Finland 78,106, Norway 88,455, and Sweden 181,754). Adjusted survival analyses were performed using Cox regression models with revision due to infection as the endpoint. The effect of risk factors such as the year of surgery, age, sex, diagnosis, type of prosthesis, and fixation were assessed. Results 2,778 (0.6%) of the primary THAs were revised due to infection. Compared to the period 1995–1999, the relative risk (with 95% CI) of revision due to infection was 1.1 (1.0–1.2) in 2000–2004 and 1.6 (1.4–1.7) in 2005–2009. Adjusted cumulative 5–year revision rates due to infection were 0.46% (0.42–0.50) in 1995–1999, 0.54% (0.50–0.58) in 2000–2004, and 0.71% (0.66–0.76) in 2005–2009. The entire increase in risk of revision due to infection was within 1 year of primary surgery, and most notably in the first 3 months. The risk of revision due to infection increased in all 4 countries. Risk factors for revision due to infection were male sex, hybrid fixation, cement without antibiotics, and THA performed due to inflammatory disease, hip fracture, or femoral head necrosis. None of these risk factors increased in incidence during the study period. Interpretation We found increased relative risk of revision and increased cumulative 5–year revision rates due to infection after primary THA during the period 1995–2009. No change in risk factors in the NARA dataset could explain this increase. We believe that there has been an actual increase in the incidence of prosthetic joint infections after THA.
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            The use of tantalum porous metal implants for Paprosky 3A and 3B defects.

            Complex acetabular defects are difficult to reconstruct. For severe pelvic defects, tantalum metal acetabular implants may provide a viable solution over traditional implants. This short-term follow-up reviews 43 acetabular revisions treated with tantalum acetabular implants. These revisions included 33 Paprosky type 3A defects, involving 30% to 50% of host acetabulum loss, and 10 type 3B defects, having similar or greater bone loss with a pelvic discontinuity. Tantulum acetabular modular augments were used in 26 cases to support the shell. At a mean of 2.8 years' follow-up, 42 components were stable, and 1 failed because of septic loosening. The overall success rate was 98%. One revision was performed because of loosening secondary to sepsis; none were performed for aseptic loosening. Implants made from highly porous tantalum metal provide a surface that is highly conducive to bone ingrowth. Combined with the ability to use modular augments for added support and stability, this technology may change the way major defects are reconstructed.
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              Applications of porous tantalum in total hip arthroplasty.

              Porous tantalum is an alternative metal for total joint arthroplasty components that offers several unique properties. Its high volumetric porosity (70% to 80%), low modulus of elasticity (3 MPa), and high frictional characteristics make it conducive to biologic fixation. Tantalum has excellent biocompatibility and is safe to use in vivo. The low modulus of elasticity allows for more physiologic load transfer and relative preservation of bone stock. Because of its bioactive nature and ingrowth properties, tantalum is used in primary as well as revision total hip arthroplasty components, with good to excellent early clinical results. In revision arthroplasty, standard and custom augments may serve as a structural bone graft substitute. Formation of a bone-like apatite coating in vivo affords strong fibrous ingrowth properties and allows for substantial soft-tissue attachment, indicating potential for use in cases requiring reattachment of muscles and tendons to a prosthesis. Development of modular components and femoral stems also is being evaluated. The initial clinical data and basic science studies support further investigation of porous tantalum as an alternative to traditional implant materials.
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                Author and article information

                Journal
                Acta Orthop
                Acta Orthop
                IORT
                iort20
                Acta Orthopaedica
                Taylor & Francis
                1745-3674
                1745-3682
                August 2019
                17 April 2019
                : 90
                : 4
                : 312-317
                Affiliations
                [a ]Department of Orthopaedic Surgery, University of Turku and Turku University Hospital , Turku;
                [b ]Department of Biostatistics, University of Turku , Turku;
                [c ]Coxa Hospital for Joint Replacement , Tampere;
                [d ]National Institute for Health and Welfare , Helsinki;
                [e ]Department of Orthopaedics and Traumatology, Oulu University Hospital , Oulu;
                [f ]Department of Orthopaedics and Traumatology, Kuopio University Hospital , Kuopio;
                [g ]Orton Hospital , Helsinki, Finland
                Author notes
                Article
                1603596
                10.1080/17453674.2019.1603596
                6718180
                30994043
                5d031fe8-a4c2-454f-9eb4-2aa8bb1e478e
                © 2019 The Author(s). Published by Taylor & Francis on behalf of the Nordic Orthopedic Federation.

                This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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                Page count
                Figures: 4, Tables: 4, Pages: 10, Words: 4740
                Categories
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                Orthopedics
                Orthopedics

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