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      Targeting for stereotactic radiosurgical thalamotomy based on tremor treatment response.

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          Abstract

          Stereotactic radiosurgery (SRS) treats severe, medically refractory essential tremor and tremor-dominant Parkinson disease. However, the optimal target for SRS treatment within the thalamic ventral intermediate nucleus (VIM) is not clearly defined. This work evaluates the precision of the physician-selected VIM target, and determines the optimal SRS target within the VIM by correlation between early responders and nonresponders.

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          Author and article information

          Journal
          Journal ID (iso-abbrev): J Neurosurg
          Title: Journal of neurosurgery
          Publisher: Journal of Neurosurgery Publishing Group (JNSPG)
          ISSN (Electronic): 1933-0693
          ISSN (Print): 0022-3085
          Publication date (Electronic): May 01 2022
          Volume: 136
          Issue: 5
          Affiliations
          [1 ] Departments of1Radiation Oncology.
          [2 ] 2Biostatistics, and.
          [3 ] 3Neurosurgery, Vanderbilt University Medical Center, Nashville, Tennessee.
          [4 ] 4Department of Neurological Surgery, University of Louisville, Kentucky; and.
          [5 ] 5Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee.
          Article
          Publisher Item ID: 2021.7.JNS21160
          DOI: 10.3171/2021.7.JNS21160
          PubMed ID: 34715657
          SO-VID: 5e9312ae-99dc-4025-84a4-e94acd7de824
          History

          Keywords: functional neurosurgery,tremor,thalamic ventral intermediate nucleus,stereotactic radiosurgery,isocenter target location,autocontouring
          Data availability:
          Keywords: functional neurosurgery, tremor, thalamic ventral intermediate nucleus, stereotactic radiosurgery, isocenter target location, autocontouring

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