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      Autochthonous disseminated dermal and visceral leishmaniasis in an AIDS patient, southern Thailand, caused by Leishmania siamensis.

      The American Journal of Tropical Medicine and Hygiene
      AIDS-Related Opportunistic Infections, complications, drug therapy, parasitology, Acquired Immunodeficiency Syndrome, Adult, Anti-HIV Agents, therapeutic use, Female, Genes, Protozoan, Humans, Lamivudine, Leishmania, genetics, isolation & purification, pathogenicity, Leishmaniasis, Cutaneous, Leishmaniasis, Visceral, Nevirapine, Phylogeny, Stavudine, Thailand, epidemiology

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          Abstract

          We report the first establishment of in vitro cultivation and genotypic characterization of Leishmania siamensis isolated from an autochthonous disseminated dermal and visceral leishmaniasis in a Thai acquired immunodeficiency syndrome (AIDS) patient. The molecular identification has shown that the parasite was identical to L. siamensis, a recently described Leishmania species reported in the southern provinces of Thailand. The phylogenetic analysis has confirmed L. siamensis as closely related to the zoonotic Leishmania species L. enrietti.

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