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      Recognition of pulmonary diseases from lung sounds using convolutional neural networks and long short-term memory

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          Abstract

          In this paper, a study is conducted to explore the ability of deep learning in recognizing pulmonary diseases from electronically recorded lung sounds. The selected data-set included a total of 103 patients obtained from locally recorded stethoscope lung sounds acquired at King Abdullah University Hospital, Jordan University of Science and Technology, Jordan. In addition, 110 patients data were added to the data-set from the Int. Conf. on Biomedical Health Informatics publicly available challenge database. Initially, all signals were checked to have a sampling frequency of 4 kHz and segmented into 5 s segments. Then, several preprocessing steps were undertaken to ensure smoother and less noisy signals. These steps included wavelet smoothing, displacement artifact removal, and z-score normalization. The deep learning network architecture consisted of two stages; convolutional neural networks and bidirectional long short-term memory units. The training of the model was evaluated based on a k-fold cross-validation scheme of tenfolds using several performance evaluation metrics including Cohen’s kappa, accuracy, sensitivity, specificity, precision, and F1-score. The developed algorithm achieved the highest average accuracy of 99.62% with a precision of 98.85% in classifying patients based on the pulmonary disease types using CNN + BDLSTM. Furthermore, a total agreement of 98.26% was obtained between the predictions and original classes within the training scheme. This study paves the way towards implementing deep learning models in clinical settings to assist clinicians in decision making related to the recognition of pulmonary diseases.

          Supplementary Information

          The online version supplementary material available at 10.1007/s12652-021-03184-y.

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          Long Short-Term Memory

          Learning to store information over extended time intervals by recurrent backpropagation takes a very long time, mostly because of insufficient, decaying error backflow. We briefly review Hochreiter's (1991) analysis of this problem, then address it by introducing a novel, efficient, gradient-based method called long short-term memory (LSTM). Truncating the gradient where this does not do harm, LSTM can learn to bridge minimal time lags in excess of 1000 discrete-time steps by enforcing constant error flow through constant error carousels within special units. Multiplicative gate units learn to open and close access to the constant error flow. LSTM is local in space and time; its computational complexity per time step and weight is O(1). Our experiments with artificial data involve local, distributed, real-valued, and noisy pattern representations. In comparisons with real-time recurrent learning, back propagation through time, recurrent cascade correlation, Elman nets, and neural sequence chunking, LSTM leads to many more successful runs, and learns much faster. LSTM also solves complex, artificial long-time-lag tasks that have never been solved by previous recurrent network algorithms.
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            A Coefficient of Agreement for Nominal Scales

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              Deep learning in neural networks: An overview

              In recent years, deep artificial neural networks (including recurrent ones) have won numerous contests in pattern recognition and machine learning. This historical survey compactly summarizes relevant work, much of it from the previous millennium. Shallow and Deep Learners are distinguished by the depth of their credit assignment paths, which are chains of possibly learnable, causal links between actions and effects. I review deep supervised learning (also recapitulating the history of backpropagation), unsupervised learning, reinforcement learning & evolutionary computation, and indirect search for short programs encoding deep and large networks.
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                Author and article information

                Contributors
                mafraiwan@just.edu.jo
                fraiwan@just.edu.jo
                1045804@students.adu.ac.ae
                1052958@students.adu.ac.ae
                Journal
                J Ambient Intell Humaniz Comput
                J Ambient Intell Humaniz Comput
                Journal of Ambient Intelligence and Humanized Computing
                Springer Berlin Heidelberg (Berlin/Heidelberg )
                1868-5137
                1868-5145
                3 April 2021
                : 1-13
                Affiliations
                [1 ]GRID grid.37553.37, ISNI 0000 0001 0097 5797, Department of Computer Engineering, , Jordan University of Science and Technology, ; P.O. Box 3030, Irbid, 22110 Jordan
                [2 ]GRID grid.37553.37, ISNI 0000 0001 0097 5797, Department of Biomedical Engineering, , Jordan University of Science and Technology, ; P.O. Box 3030, Irbid, 22110 Jordan
                [3 ]GRID grid.444459.c, ISNI 0000 0004 1762 9315, Department of Electrical and Computer Engineering, , Abu Dhabi University, ; Abu Dhabi, UAE
                Author information
                http://orcid.org/0000-0001-6352-5275
                Article
                3184
                10.1007/s12652-021-03184-y
                8019351
                33841584
                5fa6cdb6-38d9-430e-a8ff-634bd1c5f869
                © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021

                This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.

                History
                : 12 August 2020
                : 25 March 2021
                Funding
                Funded by: FundRef http://dx.doi.org/10.13039/501100004035, Jordan University of Science and Technology;
                Award ID: 20210047
                Award Recipient :
                Funded by: Abu Dhabi University Office of Research and Sponsored Programs
                Categories
                Original Research

                lung sounds,pulmonary diseases,deep learning,stethoscope,convolutional neural network,long short-term memory

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