miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques in the Tampere Vascular Study.

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Abstract

MicroRNAs are small non-coding RNAs that inversely regulate their target gene expression. The whole miRNA profile of human atherosclerotic plaques has not been studied previously. The aim of this study was to investigate the miRNA expression profile in human atherosclerotic plaques as compared to non-atherosclerotic left internal thoracic arteries (LITA), and to connect this expression to the processes in atherosclerosis.

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Journal

Journal ID (iso-abbrev): Atherosclerosis

Title: Atherosclerosis

Publisher: Elsevier BV

ISSN (Electronic): 1879-1484

ISSN (Print): 0021-9150

Publication date (Electronic): Nov 2011

Volume: 219

Issue: 1

Affiliations

[1 ] Department of Clinical Chemistry, Tampere University Hospital and the Medical School at the University of Tampere, Tampere, Finland. emma.raitoharju@uta.fi

Article

Publisher Item ID: S0021-9150(11)00641-1

DOI: 10.1016/j.atherosclerosis.2011.07.020

PubMed ID: 21820659

SO-VID: 61284cf3-ede4-4bc9-8f8f-ae38db9d4611

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