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      Risk of Hospitalized Falls and Hip Fractures in 22,103 Older Adults Receiving Mental Health Care vs 161,603 Controls: A Large Cohort Study

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          Abstract

          Objectives

          To investigate the risk of hospitalized fall or hip fracture among older adults using mental health services.

          Design

          Retrospective cohort study.

          Setting and Participants

          Residents of a South London catchment aged >60 years receiving specialist mental health care between 2008 and 2016.

          Measures

          Falls and/or a hip fracture leading to hospitalization were ascertained from linked national records. Incidence rates and incidence rate ratios (IRRs) were age- and gender-standardized to the catchment population. Multivariable survival analyses were applied investigating falls and/or hip fractures as outcomes.

          Results

          In 22,103 older adults, incidence rates were 60.1 per 1000 person-years for hospitalized falls and 13.7 per 1000 person-years for hip fractures, representing standardized IRRs of 2.17 [95% confidence interval (CI) 2.07-2.28] and 4.18 (3.79-4.60), respectively. The IRR for falls was high in those with substance-use disorder [IRR = 6.72 (5.35-8.33)], bipolar disorder [IRR = 3.62 (2.50-5.05)], depression [IRR = 2.28 (2.00-2.59)], and stress-related disorders [IRR = 2.57 (2.10-3.11)]. Hip fractures were increased in all populations (IRR > 2.5), with greatest risk in substance use disorders [IRR = 12.64 (7.22-20.52)], dementia [IRR = 4.38 (3.82-5.00)], and delirium [IRR = 4.03 (3.00-5.29)]. Comparing mental disorder subgroups with each other, after the adjustment for 25 potential confounders, patients with dementia and substance use had a significantly increased risk of falls, and patients with dementia also had an increased risk of hip fractures.

          Conclusion and Implications

          Older people using mental health services have more than double the incidence of falls and 4 times the incidence of hip fractures compared to the general population. Although incidences differ between diagnostic subgroups, all groups have a higher incidence than the general population. Targeted interventions to prevent falls and hip fractures among older adult mental health service users are urgently needed.

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          Most cited references68

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          Interventions for preventing falls in older people living in the community

          Cochrane Database of Systematic Reviews
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            • Article: found

            The Lancet Psychiatry Commission: a blueprint for protecting physical health in people with mental illness

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              • Article: not found

              Risk factors for falls in community-dwelling older people: a systematic review and meta-analysis.

              Falls are the main cause of accidental death in persons aged 65 years or older. Using MEDLINE and previous reviews, we searched for prospective studies investigating risk factors for falls among community-dwelling older people. For risk factors investigated by at least 5 studies in a comparable way, we computed pooled odds ratios (ORs) using random-effects models, with a test for heterogeneity. A total of 74 studies met the inclusion criteria and 31 risk factors were considered, including sociodemographic, mobility, sensory, psychologic, and medical factors and medication use. The strongest associations were found for history of falls (OR = 2.8 for all fallers; OR = 3.5 for recurrent fallers), gait problems (OR = 2.1; 2.2), walking aids use (OR = 2.2; 3.1), vertigo (OR = 1.8; 2.3), Parkinson disease (OR = 2.7; 2.8), and antiepileptic drug use (OR = 1.9; 2.7). For most other factors, the ORs were moderately above 1. ORs were generally higher for recurrent fallers than for all fallers. For some factors, there was substantial heterogeneity among studies. For some important factors (eg, balance and muscle weakness), we did not compute a summary estimate because the measures used in various studies were not comparable. This meta-analysis provides comprehensive evidence-based assessment of risk factors for falls in older people, confirming their multifactorial etiology. Some nonspecific indicators of high baseline risk were also strong predictors of the risk of falling.
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                Author and article information

                Contributors
                Journal
                J Am Med Dir Assoc
                J Am Med Dir Assoc
                Journal of the American Medical Directors Association
                Elsevier
                1525-8610
                1538-9375
                1 December 2020
                December 2020
                : 21
                : 12
                : 1893-1899
                Affiliations
                [a ]South London and Maudsley NHS Foundation Trust, Denmark Hill, London, United Kingdom
                [b ]Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, United Kingdom
                [c ]Research and Development Unit, Parc Sanitari Sant Joan de Déu, Universitat de Barcelona, Fundació Sant Joan de Déu, CIBERSAM, Barcelona, Spain
                [d ]ICREA, Barcelona, Spain
                [e ]Primary Care Department, Azienda ULSS (Unità Locale Socio Sanitaria) 3 “Serenissima,” Dolo, Venice, Italy
                [f ]Department of Rehabilitation Sciences, KU Leuven–University of Leuven, Leuven, Belgium
                [g ]University Psychiatric Centre, KU Leuven, University of Leuven, Kortenberg, Belgium
                [h ]NICM Health Research Institute, Western Sydney University, Sydney, New South Wales, Australia
                [i ]Division of Psychology and Mental Health, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom
                [j ]Department of Population Health Sciences, School of Population Health & Environmental Sciences, King's College London, London, United Kingdom
                [k ]University Psychiatric Centre KU Leuven, Kortenberg, Belgium
                [l ]Antwerp Health Law and Ethics Chair, University of Antwerp, Antwerp, Belgium
                Author notes
                []Address correspondence to Brendon Stubbs, PhD, MSc, MCSP, South London and Maudsley NHS Foundation Trust, Denmark Hill, London SE5 8AZ, United Kingdom. brendon.stubbs@ 123456kcl.ac.uk
                Article
                S1525-8610(20)30250-4
                10.1016/j.jamda.2020.03.005
                7723983
                32321678
                631f11f3-8051-43b1-8e36-9bdeabfc04ce
                © 2020 AMDA - The Society for Post-Acute and Long-Term Care Medicine.

                This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

                History
                Categories
                Original Study

                hip fracture,falls dementia,mental illness,schizophrenia,substance use disorder

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