Autotaxin-Lysophosphatidic Acid Pathway in Intraocular Pressure Regulation and Glaucoma Subtypes.

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Abstract

To compare the levels of autotaxin (ATX), lysophosphatidic acid (LPA), and lysophosphatidylcholine (LPC) in the aqueous humor (AH) of healthy control subjects with those of patients with different subtypes of glaucoma, and also to investigate the relationship of the ATX-LPA pathway with IOP and subtype of glaucoma.

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Journal

Journal ID (iso-abbrev): Invest. Ophthalmol. Vis. Sci.

Title: Investigative ophthalmology & visual science

Publisher: Association for Research in Vision and Ophthalmology (ARVO)

ISSN (Electronic): 1552-5783

ISSN (Print): 0146-0404

Publication date (Electronic): February 01 2018

Volume: 59

Issue: 2

Affiliations

[1 ] Department of Ophthalmology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

[2 ] Department of Clinical Laboratory Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

[3 ] CREST, Japan Science and Technology Corporation (JST), Saitama, Japan.

[4 ] Department of Clinical Laboratory, The University of Tokyo Hospital, Tokyo, Japan.

[5 ] Bioscience Division, Reagent Development Department, AIA Research Group, TOSOH Corporation, Kanagawa, Japan.

[6 ] Laboratory of Molecular and Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Miyagi, Japan.

[7 ] Hamilton Glaucoma Center, Shiley Eye Institute and Department of Ophthalmology, University of California-San Diego, La Jolla, California, United States.

Article

Publisher Item ID: 2671878

DOI: 10.1167/iovs.17-23218

PubMed ID: 29392315

SO-VID: 65d97e32-9921-437d-b661-d1616b27c3d2

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