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      Uncemented total hip arthroplasty can be used safely in the elderly population

      research-article
      , MB, BCh, FRCS(Orth) 1 , , MBBS, MCh, FRCS 1 , , MB, BCh, BSc(Hons) 2 , , MB, BCh, FRCS, MD, PhD 3 , , MSc, PhD, FRIB, FSS 4 , , MD, FRCSC 5
      Bone & Joint Open
      The British Editorial Society of Bone & Joint Surgery
      Total hip arthroplasty, Uncemented, Cemented, Elderly, Patient-reported outcome measures

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          Abstract

          Aims

          “Get It Right First Time” (GIRFT) and NHS England’s Best Practice Tariff (BPT) have published directives advising that patients over the ages of 65 (GIRFT) and 69 years (BPT) receiving total hip arthroplasty (THA) should receive cemented implants and have brought in financial penalties if this policy is not observed. Despite this, worldwide, uncemented component use has increased, a situation described as a ‘paradox’. GIRFT and BPT do, however, acknowledge more data are required to support this edict with current policies based on the National Joint Registry survivorship and implant costs.

          Methods

          This study compares THA outcomes for over 1,000 uncemented Corail/Pinnacle constructs used in all age groups/patient frailty, under one surgeon, with identical pre- and postoperative pathways over a nine-year period with mean follow-up of five years and two months (range: nine months to nine years and nine months). Implant information, survivorship, and regular postoperative Oxford Hip Scores (OHS) were collected and two comparisons undertaken: a comparison of those aged over 65 years with those 65 and under and a second comparison of those aged 70 years and over with those aged under 70.

          Results

          Overall revision rate was 1.3% (13/1,004). A greater number of revisions were undertaken in those aged over 65 years, but numbers were small and did not reach significance. The majority of revisions were implant-independent. Single component analysis revealed a 99.9% and 99.6% survival for the uncemented cup and femoral component, respectively. Mean patient-reported outcome measures (PROMs) improvement for all ages outperformed the national PROMs and a significantly greater proportion of those aged over 65/69 years reached and maintained a meaningful improvement in their OHS earlier than their younger counterparts (p < 0.05/0.01 respectively).

          Conclusion

          This study confirms that this uncemented THA system can be used safely and effectively in patient groups aged over 65 years and those over 69 years, with low complication and revision rates.

          Cite this article: Bone Jt Open 2021;2(5):293–300.

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          Most cited references34

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          Meaningful changes for the Oxford hip and knee scores after joint replacement surgery

          Objectives To present estimates of clinically meaningful or minimal important changes for the Oxford Hip Score (OHS) and the Oxford Knee Score (OKS) after joint replacement surgery. Study Design and Setting Secondary data analysis of the NHS patient-reported outcome measures data set that included 82,415 patients listed for hip replacement surgery and 94,015 patients listed for knee replacement surgery was performed. Results Anchor-based methods revealed that meaningful change indices at the group level [minimal important change (MIC)], for example in cohort studies, were ∼11 points for the OHS and ∼9 points for the OKS. For assessment of individual patients, receiver operating characteristic analysis produced MICs of 8 and 7 points for OHS and OKS, respectively. Additionally, the between group minimal important difference (MID), which allows the estimation of a clinically relevant difference in change scores from baseline when comparing two groups, that is, for clinical trials, was estimated to be ∼5 points for both the OKS and the OHS. The distribution-based minimal detectable change (MDC90) estimates for the OKS and OHS were 4 and 5 points, respectively. Conclusion This study has produced and discussed estimates of minimal important change/difference for the OKS/OHS. These estimates should be used in the power calculations and the interpretation of studies using the OKS and OHS. The MDC90 (∼4 points OKS and ∼5 points OHS) represents the smallest possible detectable change for each of these instruments, thus indicating that any lower value would fall within measurement error.
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            The direct anterior approach in total hip arthroplasty: a systematic review of the literature.

            The most effective surgical approach for total hip arthroplasty (THA) remains controversial. The direct anterior approach may be associated with a reduced risk of dislocation, faster recovery, reduced pain and fewer surgical complications. This systematic review aims to evaluate the current evidence for the use of this approach in THA.
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              Uncemented and cemented primary total hip arthroplasty in the Swedish Hip Arthroplasty Register

              Background and purpose Since the introduction of total hip arthroplasty (THA) in Sweden, both components have most commonly been cemented. A decade ago the frequency of uncemented fixation started to increase, and this change in practice has continued. We therefore analyzed implant survival of cemented and uncemented THA, and whether the modes of failure differ between the two methods of fixation. Patients and methods All patients registered in the Swedish Hip Arthroplasty Register between 1992 and 2007 who received either totally cemented or totally uncemented THA were identified (n = 170,413). Kaplan-Meier survival analysis with revision of any component, and for any reason, as the endpoints was performed. Cox regression models were used to calculate risk ratios (RRs) for revision for various reasons, adjusted for sex, age, and primary diagnosis. Results Revision-free 10-year survival of uncemented THA was lower than that of cemented THA (85% vs. 94%, p < 0.001). No age or diagnosis groups benefited from the use of uncemented fixation. Cox regression analysis confirmed that uncemented THA had a higher risk of revision for any reason (RR = 1.5, 95% CI: 1.4–1.6) and for aseptic loosening (RR = 1.5, CI: 1.3–1.6). Uncemented cup components had a higher risk of cup revision due to aseptic loosening (RR = 1.8, CI: 1.6–2.0), whereas uncemented stem components had a lower risk of stem revision due to aseptic loosening (RR = 0.4, CI: 0.3–0.5) when compared to cemented components. Uncemented stems were more frequently revised due to periprosthetic fracture during the first 2 postoperative years than cemented stems (RR = 8, CI: 5–14). The 5 most common uncemented cups had no increased risk of revision for any reason when compared with the 5 most commonly used cemented cups (RR = 0.9, CI: 0.6–1.1). There was no significant difference in the risk of revision due to infection between cemented and uncemented THA. Interpretation Survival of uncemented THA is inferior to that of cemented THA, and this appears to be mainly related to poorer performance of uncemented cups. Uncemented stems perform better than cemented stems; however, unrecognized intraoperative femoral fractures may be an important reason for early failure of uncemented stems. The risk of revision of the most common uncemented cup designs is similar to that of cemented cups, indicating that some of the problems with uncemented cup fixation may have been solved.
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                Author and article information

                Contributors
                Role: Consultant Orthopaedic Surgeon
                Role: Senior Clinical Fellow
                Role: Foundation Year 1 Doctor
                Role: Professor of Health Sciences
                Role: Professor of Biomedical Sciences and Biostatistics
                Role: Professor of Surgery
                Journal
                Bone Jt Open
                Bone Jt Open
                BJO
                Bone & Joint Open
                The British Editorial Society of Bone & Joint Surgery (London )
                2633-1462
                04 May 2021
                May 2021
                : 2
                : 5
                : 293-300
                Affiliations
                [1 ] org-divisionPrince Charles and Royal Glamorgan Hospitals, Cwm Taf Morgannwg University Health Board , South Wales, UK
                [2 ] org-divisionLeeds General Infirmary , Leeds, UK
                [3 ] org-divisionFaculty of Life Sciences and Education , org-divisionUniversity of South Wales , Pontypridd, UK
                [4 ] org-divisionBiomedical Sciences Department , org-divisionCardiff Metropolitan University , Cardiff, UK
                [5 ] org-divisionDivision of Orthopaedics , org-divisionSt Michael’s Hospital , Toronto, Canada
                Author notes
                Correspondence should be sent to Peter M. Lewis. E-mail: peter.lewis5@ 123456wales.nhs.uk
                Article
                BJO-2-293
                10.1302/2633-1462.25.BJO-2021-0006
                8168545
                33940937
                662631d0-2e24-424a-9c1b-988606c7ab0f
                © 2021 Author(s) et al.

                This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (CC BY-NC-ND 4.0) licence, which permits the copying and redistribution of the work only, and provided the original author and source are credited. See https://creativecommons.org/licenses/by-nc-nd/4.0/.

                History
                Categories
                Hip
                Hip
                Arthroplasty
                Reverse Hybrid
                Hip, hip
                Custom metadata
                Prince Charles and Royal Glamorgan Hospitals, South Wales, UK
                Hip
                None declared.

                total hip arthroplasty,uncemented,cemented,elderly,patient-reported outcome measures

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