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      Clinical Study of Heparin-Free Hemodialysis with the Inside of Hollow Fibers in Dialyzer Coated by Human Albumins

      a , b


      S. Karger AG

      Renal failure, Heparin-free, Hemodialysis, Albumins, Scanning electron microscopy

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          Background/Objective: To investigate the therapeutics of heparin-free hemodialysis (HD) with the inside of hollow fibers in a dialyzer coated with human albumins (HFHd-A1). Methods: Clinical contrast study between HFHd-A1 and heparin-free HD with hollow fibers in dialyzer by normal saline flush (HFHd-NS) was performed by adopting the cross-over design method. The dialysis effect, the effect on life signs, blood platelet functions, change of dialyzer fiber-bundle volume, appearance image, and image of scanning electron microscopy of the inside of hollow fibers in dialyzer after dialysis and the biocompatibility of dialyzer of two HD methods were compared. Results: HFHd-A1 could overcome all shortcomings of HFHd-NS and had more merits and increased expenses for HFHd-A1 were not high. Conclusion: HFHd-A1 was an effective and feasible method which could salvage patients with bleeding diseases or bleeding tendency and who need HD.

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          Author and article information

          S. Karger AG
          October 2002
          18 October 2002
          : 92
          : 4
          : 925-928
          aDepartment of Nephrology, The Fifth Affiliated Hospital, Zhong Shan University, Zhuhai City, and bDepartment of Nephrology, Guangdong Farm Center Hospital, Zhanjiang City, Republic of China
          65437 Nephron 2002;92:925–928
          © 2002 S. Karger AG, Basel

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          Page count
          Tables: 2, References: 5, Pages: 4
          Self URI (application/pdf): https://www.karger.com/Article/Pdf/65437
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