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Abstract
<p class="first" id="P2">The foundation for a new era of data-driven medicine has
been set by recent technological
advances that enable the assessment and management of human health at an unprecedented
level of resolution – what we refer to as high definition medicine. Our ability to
assess human health in high definition is enabled, in part, by advances in DNA sequencing,
physiological and environmental monitoring, advanced imaging and behavioral tracking.
Our ability to understand and act upon these observations at equally high precision
is driven by advances in genome editing, cellular reprogramming, tissue engineering,
and information technologies, especially artificial intelligence. In this review,
we will examine the core disciplines that enable high definition medicine, and project
how these technologies will alter the future of medicine.
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