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Modification of cut-off values for HE4, CA125 and the ROMA algorithm for early-stage epithelial ovarian cancer detection: Results from 1021 cases in South China
Ying Xu ,
Rihui Zhong ,
Jian He ,
Rui Ding ,
Haixiong Lin ,
Yawen Deng ,
Lijun Zhou ,
Xiaohui Li ,
Junyi Jiang ,
Yunwen Bao ,
Xiaohong Luo ,
Chaohui Duan
January 2016
January 2016
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Abstract
<p class="first" id="d904107e161">The purpose of this study was to evaluate the performance
of human epididymis protein
4 (HE4) and the Risk of Ovarian Malignancy Algorithm (ROMA) in early stage epithelial
ovarian cancer (EOC) detection in patients in southern China. Additionally, this study
proposes a possible ideal cut-off value for each marker to its own population in South
China.
</p>