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      Scalability of mobile technology interventions in the prevention and management of HIV among adolescents in low-income and middle-income countries: protocol for a systematic review

      systematic-review

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          Abstract

          Introduction

          The rate of new infections with HIV remains high among adolescents globally. Adolescents in low-income and middle-income countries (LMICs), who are least likely to have access to quality healthcare, have the highest proportion of those living with HIV. Mobile technology has played an important role in providing access to information and services among adolescents in recent years. This review aims to synthesise and summarise information that will be useful in the planning, designing and implementing of future mHealth strategies.

          Methods and analysis

          Interventional studies, reported in English, on the prevention and management of HIV among adolescents that used mobile technology in LMICs will be included. MEDLINE (via PubMed), Embase, Web of Science, CINAHL, Clinicaltrials.gov, WHO International Clinical Trials Registry Platform (ICTRP), and the Cochrane Library are the information sources that have been identified as relevant to the area of study. These sources will be searched from inception to March 2023. The risk of bias will be assessed using the Cochrane Risk of Bias tool. The scalability of each study will be assessed using the Intervention Scalability Assessment Tool. Two independent reviewers will conduct the selection of studies, data extraction, and assessment of the risk of bias and scalability. A narrative synthesis of all the included studies will be done.

          Ethics and dissemination

          Ethical approval was not necessary for this study. This is a systematic review of publicly available information and therefore ethical approval was not deemed necessary. The results of this review will be published in a peer reviewed journal.

          Trial registration

          This protocol has been registered with the International Prospective Register of Systematic Reviews (PROSPERO), registration number CRD42022362130.

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          Most cited references28

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          Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement.

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            RoB 2: a revised tool for assessing risk of bias in randomised trials

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              Gray literature: An important resource in systematic reviews

              Systematic reviews aide the analysis and dissemination of evidence, using rigorous and transparent methods to generate empirically attained answers to focused research questions. Identifying all evidence relevant to the research questions is an essential component, and challenge, of systematic reviews. Gray literature, or evidence not published in commercial publications, can make important contributions to a systematic review. Gray literature can include academic papers, including theses and dissertations, research and committee reports, government reports, conference papers, and ongoing research, among others. It may provide data not found within commercially published literature, providing an important forum for disseminating studies with null or negative results that might not otherwise be disseminated. Gray literature may thusly reduce publication bias, increase reviews' comprehensiveness and timeliness, and foster a balanced picture of available evidence. Gray literature's diverse formats and audiences can present a significant challenge in a systematic search for evidence. However, the benefits of including gray literature may far outweigh the cost in time and resource needed to search for it, and it is important for it to be included in a systematic review or review of evidence. A carefully thought out gray literature search strategy may be an invaluable component of a systematic review. This narrative review provides guidance about the benefits of including gray literature in a systematic review, and sources for searching through gray literature. An illustrative example of a search for evidence within gray literature sources is presented to highlight the potential contributions of such a search to a systematic review. Benefits and challenges of gray literature search methods are discussed, and recommendations made.
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                Author and article information

                Journal
                BMJ Open
                BMJ Open
                bmjopen
                bmjopen
                BMJ Open
                BMJ Publishing Group (BMA House, Tavistock Square, London, WC1H 9JR )
                2044-6055
                2023
                14 July 2023
                : 13
                : 7
                : e069362
                Affiliations
                [1 ]departmentInstitute of Child Health , Ringgold_113092University of Ibadan College of Medicine , Ibadan, Nigeria
                [2 ]departmentGlobal and Community Health , Ringgold_49340George Mason University College of Health and Human Services , Fairfax, Virginia, USA
                [3 ]departmentMedicine , University of Ibadan, University College Hospital , Ibadan, Nigeria
                [4 ]departmentGlobal Health and Population , Harvard School of Public Health , Boston, Massachusetts, USA
                Author notes
                [Correspondence to ] Dr Emmanuel S Adebayo; esadebayo@ 123456com.ui.edu.ng
                Author information
                http://orcid.org/0000-0002-9148-4236
                http://orcid.org/0000-0003-3369-5972
                http://orcid.org/0000-0003-4372-9822
                http://orcid.org/0000-0002-2946-8956
                http://orcid.org/0000-0002-2908-600X
                Article
                bmjopen-2022-069362
                10.1136/bmjopen-2022-069362
                10351258
                37451733
                6923acef-d694-43f4-891d-184aa3a6c59a
                © Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

                This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See:  http://creativecommons.org/licenses/by-nc/4.0/.

                History
                : 21 October 2022
                : 19 June 2023
                Funding
                Funded by: National Institute of Child Health & Human Development (NICHD);
                Award ID: D43 TW010543
                Funded by: FundRef http://dx.doi.org/10.13039/100000061, Fogarty International Center;
                Award ID: D43 TW010543
                Categories
                HIV/AIDS
                1506
                Protocol
                Custom metadata
                unlocked

                Medicine
                hiv & aids,public health,preventive medicine
                Medicine
                hiv & aids, public health, preventive medicine

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