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      Quantum Machine Learning Architecture for COVID-19 Classification Based on Synthetic Data Generation Using Conditional Adversarial Neural Network

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          Abstract

          Background

          COVID-19 is a novel virus that affects the upper respiratory tract, as well as the lungs. The scale of the global COVID-19 pandemic, its spreading rate, and deaths are increasing regularly. Computed tomography (CT) scans can be used carefully to detect and analyze COVID-19 cases. In CT images/scans, ground-glass opacity (GGO) is found in the early stages of infection. While in later stages, there is a superimposed pulmonary consolidation.

          Methods

          This research investigates the quantum machine learning (QML) and classical machine learning (CML) approaches for the analysis of COVID-19 images. The recent developments in quantum computing have led researchers to explore new ideas and approaches using QML. The proposed approach consists of two phases: in phase I, synthetic CT images are generated through the conditional adversarial network (CGAN) to increase the size of the dataset for accurate training and testing. In phase II, the classification of COVID-19/healthy images is performed, in which two models are proposed: CML and QML.

          Result

          The proposed model achieved 0.94 precision (Pn), 0.94 accuracy (Ac), 0.94 recall (Rl), and 0.94 F1-score (Fe) on POF Hospital dataset while 0.96 Pn, 0.96 Ac, 0.95 Rl, and 0.96 Fe on UCSD-AI4H dataset.

          Conclusion

          The proposed method achieved better results when compared to the latest published work in this domain.

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          Most cited references25

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          Is Open Access

          A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version)

          In December 2019, a new type viral pneumonia cases occurred in Wuhan, Hubei Province; and then named “2019 novel coronavirus (2019-nCoV)” by the World Health Organization (WHO) on 12 January 2020. For it is a never been experienced respiratory disease before and with infection ability widely and quickly, it attracted the world’s attention but without treatment and control manual. For the request from frontline clinicians and public health professionals of 2019-nCoV infected pneumonia management, an evidence-based guideline urgently needs to be developed. Therefore, we drafted this guideline according to the rapid advice guidelines methodology and general rules of WHO guideline development; we also added the first-hand management data of Zhongnan Hospital of Wuhan University. This guideline includes the guideline methodology, epidemiological characteristics, disease screening and population prevention, diagnosis, treatment and control (including traditional Chinese Medicine), nosocomial infection prevention and control, and disease nursing of the 2019-nCoV. Moreover, we also provide a whole process of a successful treatment case of the severe 2019-nCoV infected pneumonia and experience and lessons of hospital rescue for 2019-nCoV infections. This rapid advice guideline is suitable for the first frontline doctors and nurses, managers of hospitals and healthcare sections, community residents, public health persons, relevant researchers, and all person who are interested in the 2019-nCoV.
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            Artificial intelligence in healthcare

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              Lung Pattern Classification for Interstitial Lung Diseases Using a Deep Convolutional Neural Network.

              Automated tissue characterization is one of the most crucial components of a computer aided diagnosis (CAD) system for interstitial lung diseases (ILDs). Although much research has been conducted in this field, the problem remains challenging. Deep learning techniques have recently achieved impressive results in a variety of computer vision problems, raising expectations that they might be applied in other domains, such as medical image analysis. In this paper, we propose and evaluate a convolutional neural network (CNN), designed for the classification of ILD patterns. The proposed network consists of 5 convolutional layers with 2 × 2 kernels and LeakyReLU activations, followed by average pooling with size equal to the size of the final feature maps and three dense layers. The last dense layer has 7 outputs, equivalent to the classes considered: healthy, ground glass opacity (GGO), micronodules, consolidation, reticulation, honeycombing and a combination of GGO/reticulation. To train and evaluate the CNN, we used a dataset of 14696 image patches, derived by 120 CT scans from different scanners and hospitals. To the best of our knowledge, this is the first deep CNN designed for the specific problem. A comparative analysis proved the effectiveness of the proposed CNN against previous methods in a challenging dataset. The classification performance ( ~ 85.5%) demonstrated the potential of CNNs in analyzing lung patterns. Future work includes, extending the CNN to three-dimensional data provided by CT volume scans and integrating the proposed method into a CAD system that aims to provide differential diagnosis for ILDs as a supportive tool for radiologists.
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                Author and article information

                Contributors
                sharif@ciitwah.edu.pk
                Journal
                Cognit Comput
                Cognit Comput
                Cognitive Computation
                Springer US (New York )
                1866-9956
                1866-9964
                10 August 2021
                : 1-12
                Affiliations
                [1 ]GRID grid.442867.b, ISNI 0000 0004 0401 3861, Department of Computer Science, , University of Wah, ; 47040, Wah Cantt, Pakistan
                [2 ]GRID grid.418920.6, ISNI 0000 0004 0607 0704, Department of Computer Science, , COMSATS University Islamabad, ; Wah Campus, 47040, Wah Cantt, Pakistan
                [3 ]GRID grid.412956.d, MBBS, FCPS Diagnostic Radiology, Consultant Radiologist POF Hospital and Associate Professor Radiology Wah Medical College, ; Wah Cantt, Pakistan
                [4 ]Faculty of Applied Computing and Technology, Noroff University College, Kristiansand, Norway
                [5 ]GRID grid.418391.6, ISNI 0000 0001 1015 3164, Birla Institute of Technology, ; Mesra, Jharkhand India
                Article
                9926
                10.1007/s12559-021-09926-6
                8353617
                692b859f-415a-4f30-b581-a2162c011fc5
                © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021

                This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.

                History
                : 21 January 2021
                : 23 July 2021
                Categories
                Article

                Neurosciences
                cgan,relu,softmax,classical machine learning,quanvolutional neural network
                Neurosciences
                cgan, relu, softmax, classical machine learning, quanvolutional neural network

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