Combination of doxorubicin with harmine-loaded liposomes exerting synergistic antitumor efficacy.

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Abstract

Long-circulation (PEGLip), pH-sensitive (PEOzLip), and active targeted liposomes (PEG-TATLip)-loading doxorubicin (DOX) and harmine (HM) were prepared. Their physicochemical properties and antitumor effect were investigated.

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Author and article information

Journal

Journal ID (iso-abbrev): Drug Dev Ind Pharm

Title: Drug development and industrial pharmacy

Publisher: Informa UK Limited

ISSN (Electronic): 1520-5762

ISSN (Print): 0363-9045

Publication date (Electronic): Apr 2018

Volume: 44

Issue: 4

Affiliations

[1 ] a Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, Department of Pharmaceutics, School of Pharmaceutical Sciences , Peking University , Beijing , China.