Analysis of the formation mechanism and occurrence possibility of Post-Stenotic Dilatation of the aorta by CFD approach.

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Abstract

Post-Stenotic Dilatation (PSD), the common complication of coarctation of the aorta (COA), is a progressive disease involving aortic aneurysm and even rupture. However, there has been no definitive method that could investigate the mechanism of PSD formation, progression and rupture. The purpose of the present work is to analyze the mechanism behind PSD formation and to further assess the risk of COA patients with different coarctation degrees deteriorating into PSD.

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Journal

Journal ID (iso-abbrev): Comput Methods Programs Biomed

Title: Computer methods and programs in biomedicine

Publisher: Elsevier BV

ISSN (Electronic): 1872-7565

ISSN (Print): 0169-2607

Publication date (Electronic): Oct 2020

Volume: 194

Affiliations

[1 ] School of Energy and Environmental Engineering, University of Science and Technology Beijing, Beijing 10083, China; School of Mathematics and Physics, University of Science and Technology Beijing, Beijing 100083, China.

[2 ] Department of Vascular Surgery, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.

[3 ] Department of Vascular Surgery, the Second Xiangya Hospital, Central South University, Changsha, 410000, China.

[4 ] School of Mathematics and Physics, University of Science and Technology Beijing, Beijing 100083, China. Electronic address: liancunzheng@ustb.edu.cn.

[5 ] Department of Vascular Surgery, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China. Electronic address: changshu01@yahoo.com.

Article

Publisher Item ID: S0169-2607(20)30781-1

DOI: 10.1016/j.cmpb.2020.105522

PubMed ID: 32422474

SO-VID: 696c820b-4cc5-4223-a4f1-3f7b4bf80d29

History

Keywords: Aorta with different coarctation degrees,Hemodynamics,Post-Stenotic Dilatation of the aorta,Pre- and post-operation,Vortical structures

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Keywords: Aorta with different coarctation degrees, Hemodynamics, Post-Stenotic Dilatation of the aorta, Pre- and post-operation, Vortical structures

Analysis of the formation mechanism and occurrence possibility of Post-Stenotic Dilatation of the aorta by CFD approach.

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