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Abstract
Sleep disturbance is very common in patients with atopic dermatitis (AD) and is a
major factor leading to impaired quality of life. Sleep disturbance is often viewed
as one of the symptoms of AD and one of the measures of disease severity. In this
review we describe a variety of sleep disorders associated with AD and a wide range
of effect that sleep disorders have on patients with AD. We also discuss our current
understanding of the mechanism of sleep disturbance in patients with AD. The relationship
between sleep disorders and AD might be bidirectional and could form a vicious cycle.
Therefore we suggest viewing sleep disorders as a comorbidity of AD for which regular
screening and bidirectional management strategies are indicated, with equal focus
on maintaining disease control and implementing specific strategies to improve sleep.