- Record: found
- Abstract: not found
- Article: not found
Genome and transcriptome biomarkers of response to immune checkpoint inhibitors in advanced solid tumours
Alexandra Pender ,
Emma Titmuss ,
Erin D Pleasance ,
Kevin Y Fan ,
Hillary Pearson ,
Scott D Brown ,
Cameron J Grisdale ,
James T. Topham ,
Yaoqing Shen ,
Melika Bonakdar ,
Greg Taylor ,
Laura M Williamson ,
Karen L Mungall ,
Eric Chuah ,
Andrew J. Mungall ,
Richard A Moore ,
Jean-Michel Lavoie ,
Stephen Yip ,
Howard Lim ,
Daniel J Renouf ,
Sophie Sun ,
Robert A. Holt ,
Steven JM Jones ,
Marco A. Marra ,
Janessa Laskin
October 05 2020
Read this article at
There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.
Abstract
<p class="first" id="d1568033e301">Immune checkpoint inhibitors (ICI) have revolutionized
the treatment of solid tumors
with dramatic and durable responses seen across multiple tumor types. However, identifying
patients who will respond to these drugs remains challenging, particularly in the
context of advanced and previously treated cancers.
</p>