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Abstract
5-(Chloromethyl)furfural (CMF) is a disruptive innovation in the biorefinery. Chemically,
it is at least as versatile as the well-known HMF but, unlike HMF, it is accessible
in high yield directly from cellulosic biomass due to its lipophilicity and stability
under acidic conditions, which facilitate isolation. It has a rich derivative chemistry
that includes biofuels, renewable polymers, specialty chemicals, and value-added agrochemical
and pharmaceutical products.