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Eucommia ulmoides Oliv.: ethnopharmacology, phytochemistry and pharmacology of an important traditional Chinese medicine.
Xirui He
1 ,
Jinhui Wang
2 ,
Maoxing Li
3 ,
Dingjun Hao
1 ,
Yan Yang
4 ,
Chunling Zhang
1 ,
Rui He
1 ,
Rui Tao
5
2014
1, 1-diphenyl-2-picrylhydrazyl,
50% inhibition concentration,
AChE,
AD,
AIDS,
AST,
Alzheimer's disease,
Ang II,
Anti-hypertensive activity,
BAT-SNA,
Brown adipose tissue sympathetic nerve activity,
CJ-S (131),
CNKI,
COX-2,
Campylobacter jejuni enteritis 131,
China National Knowledge Infrastructure,
DPPH,
EC50,
EDTA,
ELE,
ELISA,
Ethnopharmacology,
Eucommia ulmoides,
FFA,
GRd,
GSH,
GST,
GVNA,
HDL,
HIV,
HL-60,
HMG-CoA,
Hypolipidemic activity,
IC50,
ID,
IL,
LDL,
LPS,
Lignans,
MMC,
MeOH,
NO,
OVX,
PAGE,
PDE,
ROS,
SD,
SHRs,
SOD,
STZ,
Sprague-Dawley,
TAG,
TCM,
TFAs,
THP-1 cells,
TNF-α,
Tk gene,
UPLC,
UPLC-ESI-MS,
WAT-SNA,
acetylcholinesterase,
acquired immunodeficiency syndrome,
angiotensin II,
aspartate transaminase,
cAMP,
concentration for 50% of maximal effect,
cyclic adenosine monophosphate,
cyclooxygenase-2,
enzyme-linked immunosorbent assay,
ethylenediaminetetraacetic acid,
extracts of leaves from Eucommia ulmoides Oliv.,
free fatty acids,
gastric vagal nerve activity,
glucocorticoid receptor,
glutathione,
glutathione S-transferase,
high density lipoprotein,
human acute monocytic leukemia cell line,
human immunodeficiency virus infection,
human promyelocytic leukemia cells,
hydroxy methylglutaryl coenzyme A,
interleukin,
intraduodenal,
lipopolysaccharide,
low density lipoprotein,
methyl alcohol,
mitomycin C,
nNOS,
neuronal nitric oxide synthase,
nitric oxide,
ovariectomy,
phosphodiesterase,
polyacrylamide gel electrophoresis,
reactive oxygen species,
spontaneously hypertensive rats,
streptozotocin,
superoxide dismutase,
thymidine kinase gene,
total fatty acids,
traditional Chinese Medicine,
tumor necrosis factor-α,
tumor-associated glycoprotein,
ultra performance liquid chromatography,
ultra performance liquid chromatography with electrospray ionization-tandem mass spectrometry,
white adipose tissue sympathetic nerve activity
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Abstract
Eucommia ulmoides Oliv. (Family Eucommiaceae), also known as Dù-zhòng (Chinese: ), Tuchong (in Japanese), is the sole species of the genus Eucommia. The leaf, stem, and bark as well as staminate flower of Eucommia ulmoides have been traditionally used to cure many diseases in China, Japan, Korea, among others. The aim of this review is to comprehensively outline the botanical description, ethnopharmacology, phytochemistry, biological activities, and toxicology of Eucommia ulmoides and to discuss possible trends for further study of Eucommia ulmoides.
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Author and article information
PDE,PAGE,CNKI,OVX,tumor-associated glycoprotein,NO,CJ-S (131),MeOH,thymidine kinase gene,MMC,superoxide dismutase,streptozotocin,Lignans,AD,total fatty acids,traditional Chinese Medicine,tumor necrosis factor-α,ultra performance liquid chromatography,ultra performance liquid chromatography with electrospray ionization-tandem mass spectrometry,white adipose tissue sympathetic nerve activity,1, 1-diphenyl-2-picrylhydrazyl,50% inhibition concentration,AChE,spontaneously hypertensive rats,reactive oxygen species,LPS,Brown adipose tissue sympathetic nerve activity,BAT-SNA,polyacrylamide gel electrophoresis,phosphodiesterase,LDL,ovariectomy,nitric oxide,IL,Anti-hypertensive activity,neuronal nitric oxide synthase,nNOS,ID,mitomycin C,low density lipoprotein,methyl alcohol,IC50,Ang II,lipopolysaccharide,Hypolipidemic activity,intraduodenal,high density lipoprotein,interleukin,HMG-CoA,hydroxy methylglutaryl coenzyme A,gastric vagal nerve activity,human promyelocytic leukemia cells,human immunodeficiency virus infection,enzyme-linked immunosorbent assay,human acute monocytic leukemia cell line,HL-60,HIV,Alzheimer's disease,AST,glutathione S-transferase,HDL,glutathione,glucocorticoid receptor,GVNA,AIDS,free fatty acids,GST,TNF-α,THP-1 cells,extracts of leaves from Eucommia ulmoides Oliv.,TFAs,Tk gene,UPLC,UPLC-ESI-MS,WAT-SNA,acetylcholinesterase,acquired immunodeficiency syndrome,angiotensin II,aspartate transaminase,cAMP,concentration for 50% of maximal effect,cyclic adenosine monophosphate,cyclooxygenase-2,Sprague-Dawley,ethylenediaminetetraacetic acid,GSH,COX-2,Campylobacter jejuni enteritis 131,China National Knowledge Infrastructure,DPPH,EC50,EDTA,ELE,ELISA,Ethnopharmacology,Eucommia ulmoides,FFA,GRd,TCM,TAG,STZ,SOD,SHRs,SD,ROS
PDE, PAGE, CNKI, OVX, tumor-associated glycoprotein, NO, CJ-S (131), MeOH, thymidine kinase gene, MMC, superoxide dismutase, streptozotocin, Lignans, AD, total fatty acids, traditional Chinese Medicine, tumor necrosis factor-α, ultra performance liquid chromatography, ultra performance liquid chromatography with electrospray ionization-tandem mass spectrometry, white adipose tissue sympathetic nerve activity, 1, 1-diphenyl-2-picrylhydrazyl, 50% inhibition concentration, AChE, spontaneously hypertensive rats, reactive oxygen species, LPS, Brown adipose tissue sympathetic nerve activity, BAT-SNA, polyacrylamide gel electrophoresis, phosphodiesterase, LDL, ovariectomy, nitric oxide, IL, Anti-hypertensive activity, neuronal nitric oxide synthase, nNOS, ID, mitomycin C, low density lipoprotein, methyl alcohol, IC50, Ang II, lipopolysaccharide, Hypolipidemic activity, intraduodenal, high density lipoprotein, interleukin, HMG-CoA, hydroxy methylglutaryl coenzyme A, gastric vagal nerve activity, human promyelocytic leukemia cells, human immunodeficiency virus infection, enzyme-linked immunosorbent assay, human acute monocytic leukemia cell line, HL-60, HIV, Alzheimer's disease, AST, glutathione S-transferase, HDL, glutathione, glucocorticoid receptor, GVNA, AIDS, free fatty acids, GST, TNF-α, THP-1 cells, extracts of leaves from Eucommia ulmoides Oliv., TFAs, Tk gene, UPLC, UPLC-ESI-MS, WAT-SNA, acetylcholinesterase, acquired immunodeficiency syndrome, angiotensin II, aspartate transaminase, cAMP, concentration for 50% of maximal effect, cyclic adenosine monophosphate, cyclooxygenase-2, Sprague-Dawley, ethylenediaminetetraacetic acid, GSH, COX-2, Campylobacter jejuni enteritis 131, China National Knowledge Infrastructure, DPPH, EC50, EDTA, ELE, ELISA, Ethnopharmacology, Eucommia ulmoides, FFA, GRd, TCM, TAG, STZ, SOD, SHRs, SD, ROS