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      Complete vs Culprit-Lesion-Only Revascularization for ST-Segment Elevation Myocardial Infarction : A Systematic Review and Meta-analysis

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          Abstract

          <p class="first" id="d5936367e200">Recently, the Complete vs Culprit-Only Revascularization to Treat Multivessel Disease After Early PCI (percutaneous coronary intervention) for STEMI (ST-segment elevation myocardial infarction [MI]) (COMPLETE) trial showed that angiography-guided PCI of the nonculprit lesion with the goal of complete revascularization reduced cardiovascular (CV) death or new MI compared with PCI of the culprit lesion only in STEMI. Whether complete revascularization also reduces CV mortality is uncertain. Moreover, whether the association of complete revascularization with hard clinical outcomes is consistent when fractional flow reserve (FFR)- and angiography-guided strategies are used is unknown. </p>

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          Author and article information

          Journal
          JAMA Cardiology
          JAMA Cardiol
          American Medical Association (AMA)
          2380-6583
          May 20 2020
          Affiliations
          [1 ]Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Alberta, Canada
          [2 ]The Heart Center, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
          [3 ]Department of Cardiology, Maasstad Ziekenhuis, Rotterdam, the Netherlands
          [4 ]Department of Cardiovascular Sciences, University of Leicester and NIHR (National Institute of Heath Research) Leicester Cardiovascular Biomedical Research Unit, University Hospitals of Leicester NHS (National Health Service) Trust, Glenfield Hospital, Leicester, United Kingdom
          [5 ]Department of Medical Sciences, Uppsala University, Uppsala, Sweden
          [6 ]Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom
          [7 ]Centre for Cardiovascular Innovation, University of British Columbia, Vancouver, British Columbia, Canada
          [8 ]Zena and Michael A. Weiner Cardiovascular Institute, Mount Sinai School of Medicine, New York, New York
          [9 ]Division of Cardiology, University of British Columbia, Vancouver, British Columbia, Canada
          [10 ]Population Health Research Institute, Hamilton Health Sciences, McMaster University, Hamilton, Ontario, Canada
          Article
          10.1001/jamacardio.2020.1251
          7240651
          32432651
          714ff39d-3bc7-4014-9a9e-edc06fe31204
          © 2020
          History

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