Effect of the Partial Constriction of Portal Vein on Renal Hypertension in the Rat

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Abstract

Partial constriction of the portal vein in the rat impedes the development of renal hypertension, or decreases the already developed hypertension, respectively. Taking into consideration the fact that this effect could be observed also in that experimental form (left kidney clipped, the opposite one removed) in which the renin content of the clipped kidney and the increase of plasma renin activity could never be demonstrated – and even in the other experimental form (left kidney clipped, the opposite one untouched)- the protective effect was only present when the above-mentioned increase of renin level was already normalized: it seems that the protective effect of partial constriction of the portal vein does not take place due to the possible hepatic damage leading to an angiotensinogen production in a lower degree.

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Journal ID (publisher-id): JVR

Journal ID (nlm-ta): J Vasc Res

Journal ID (doi): 10.1159/issn.1018-1172

Title: Journal of Vascular Research

Publisher: S. Karger AG

ISSN (Print): 1018-1172

ISSN (Electronic): 1423-0135

Publication date Subscription-year: 1971

Publication date (Print): 1971

Publication date (Electronic): 18 September 2008

Volume: 8

Issue: 2

Pages: 77-82

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2nd Department of Medicine, Szeged University Medical School, Szeged

Article

Publisher ID: 157862 Other ID: Angiologica 1971;8:77–82

DOI: 10.1159/000157862

SO-VID: 72ba6d5c-29b1-4905-ac13-5c701ba9e99c

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Effect of the Partial Constriction of Portal Vein on Renal Hypertension in the Rat

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Karger: Cardiovascular System

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