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      Factors associated with severe late toxicity after concurrent chemoradiation for locally advanced head and neck cancer: an RTOG analysis.

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          Abstract

          Concurrent chemoradiotherapy (CCRT) for squamous cell carcinoma of the head and neck (SCCHN) increases both local tumor control and toxicity. This study evaluates clinical factors that are associated with and might predict severe late toxicity after CCRT.

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          Author and article information

          Journal
          J Clin Oncol
          Journal of clinical oncology : official journal of the American Society of Clinical Oncology
          American Society of Clinical Oncology (ASCO)
          1527-7755
          0732-183X
          Jul 20 2008
          : 26
          : 21
          Affiliations
          [1 ] Jefferson Medical College and Kimmel Cancer Center of Thomas Jefferson University, Philadelphia, PA, USA. mitchell.machtay@jeffersonhospital.org
          Article
          JCO.2007.14.8841
          10.1200/JCO.2007.14.8841
          4911537
          18559875
          73151cfc-76c0-49f9-94db-887d29197ff3
          History

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