78
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Mioblastoma de mama

      research-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Se presenta una paciente portadora de un mioblastoma (tumor de células granulares) de la mama, tumor poco frecuente y de importante diagnóstico diferencial con el cáncer de mama, debido a su gran semejanza clínica e imagenológica. Se trata de una paciente de 66 años de edad con nódulo de 3 centímetros de diámetro en mama derecha, de 6 meses de evolución, de consistencia pétrea, bien definido, no doloroso y con cambios en la piel subyacente, con estudio mamográfico: BI-rads 4. Se realiza biopsia incisional que reporto: Mioblastoma (Tumor de células granulares). En conclusión el mioblastoma representa un reto diagnóstico para el cirujano general debido a su semejanza con patología neoplásica, se debe tener en cuenta al momento de la evaluación de pacientes con nódulos mamarios, en cuyo caso es de suma importancia el estudio anatomopatológico.

          Translated abstract

          It is presented a case of a myoblastoma (granular cell tumor) of the breast, a less frequent and important benign breast disease because it is mammographic and clinical similarities with breast cancer. A sixty year old, hispanic female, with six month history of a 3 cm palpable mass, rock-like consistence, regular, painless with skin changes, located at the upper outer quadrant of her right breast. Mammographic study Bi-rads 4 and excisional biopsy report of granular cell tumor. The myoblastoma becomes a challenging diagnosis for the general surgeon thus its similarities with the neoplasic diseases of the breast, the surgeon must remember it when evaluating a palpable mass of the breast.

          Related collections

          Most cited references30

          • Record: found
          • Abstract: found
          • Article: not found

          Malignant granular cell tumor: report of a case and review of the literature.

          The histological, immunohistochemical and electron microscopic features of a rare malignant granular cell tumor (GCT) arising in the left radial nerve of a 54-year-old man are reported. Despite a lack of local recurrence following extirpation, the tumor metastasized to the skull five years later. Light-microscopically, both primary and metastatic tumors consisted of markedly atypical or pleomorphic neoplastic cells with abundant cytoplasm containing diastase-resistant periodic acid Schiff reaction-positive granules. These tumor cells were arranged in a sheet-like pattern with mitotic figures including atypical ones, and were frequently immunopositive for proliferating cell nuclear antigen and c-MET, the c-met proto-oncogene product. These findings reflect high-grade malignancy of the present tumor. In addition, the tumor cells were positive for S-100 protein and neuron-specific enolase. Ultrastructurally, a large number of intracytoplasmic granules featuring secondary lysosomes as well as long interdigitating cytoplasmic processes, intercellular intermediate junctions, discontinuous basal lamina-like structures, and stromal long-spacing collagen were observed. These findings indicated schwannian differentiation of the present tumor. In addition, based on a review of previously reported cases, the overall clinicopathological characteristics of malignant GCT were summarized.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Case report: coincident granular cell tumour of the breast with invasive ductal carcinoma.

            Granular cell tumours of the breast are rare lesions which are almost always benign. They are of interest because their clinical, radiological and pathological appearances often closely resemble those of malignancy. A case is described in which screening mammography in an asymptomatic woman led to the diagnosis of simultaneous invasive intraductal carcinoma in one breast and benign granular cell tumour in the other. Granular cell tumour of the breast coincident with other breast tumours is very rarely described and an association with breast carcinoma is unknown.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Granular cell tumor of the breast: definitive diagnosis by sonographically guided percutaneous biopsy.

              Granular cell tumor is a rare, benign breast neoplasm that may mimic malignancy both clinically and radiologically. We present 2 cases in which granular cell tumor was initially diagnosed by sonographically guided percutaneous biopsies. Sonographic guidance confirmed needle placement during multiple passes and thereby decreased the likelihood of sampling error. A diagnosis of granular cell tumor prior to definitive resection enables optimal therapeutic planning and allows radical surgery to be avoided.
                Bookmark

                Author and article information

                Journal
                rfm
                Revista de la Facultad de Medicina
                RFM
                Universidad Central de Venezuela. Facultad de Medicina. Comisión de Publicaciones de la Facultad de Medicina (Caracas, Distrito Capital, Venezuela )
                0798-0469
                June 2004
                : 27
                : 2
                : 116-118
                Affiliations
                [02] orgnameServicio de Cirugia II. H.U.C. orgdiv1Postgrado de Cirugia General orgdiv2Cirujano General
                [03] orgnameServicio de Cirugia II. H.U.C. orgdiv1Postgrado de Cirugia General orgdiv2Cirujano General
                [01] orgnameServicio de Cirugia II. H.U.C. orgdiv1Profesor Titular
                [04] orgnameU.C.V. orgdiv1Instituto Anatomia Patologica orgdiv2Profesor Agregado
                Article
                S0798-04692004000200006 S0798-0469(04)02700206
                744970b6-94bf-4e51-86db-592c1d5a3979

                http://creativecommons.org/licenses/by/4.0/

                History
                : 01 June 2004
                : 11 October 2004
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 26, Pages: 3
                Product

                SciELO Venezuela

                Categories
                Editorial

                Tumor de células granulares,Breast cancer,Granular cell tumor,Myoblastoma,Cáncer de mama,Mioblastoma

                Comments

                Comment on this article