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      Association Between Complement Factor C2/C3/CFB/CFH Polymorphisms and Age-Related Macular Degeneration: A Meta-Analysis.

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          Abstract

          Several previous studies have assessed the contribution of polymorphisms in genes encoding the complement factors C2/C3/CFB/CFH with the risk of age-related macular degeneration (AMD), however the results have been inconsistent. We conducted a meta-analysis to systematically review the potential association between complement factor polymorphisms and AMD.

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          Author and article information

          Journal
          Journal ID (iso-abbrev): Genet Test Mol Biomarkers
          Title: Genetic testing and molecular biomarkers
          Publisher: Mary Ann Liebert Inc
          ISSN (Electronic): 1945-0257
          ISSN (Print): 1945-0257
          Publication date (Electronic): Sep 2018
          Volume: 22
          Issue: 9
          Affiliations
          [1 ] 1 Department of Biochemistry, College of Medicine, Nanchang University , Nanchang, P.R. China .
          [2 ] 2 Department of Internal Medicine, Youhao District People's Hospital , Yichun, P.R. China .
          [3 ] 3 Department of Clinical Laboratory, The Second Affiliated Hospital of Nanchang University , Nanchang, P.R. China .
          [4 ] 4 Department of Epidemiology, School of Public Health, Nanchang University , Nanchang, P.R. China .
          [5 ] 5 Jiangxi Province Key Laboratory of Preventive Medicine, School of Public Health, Nanchang University , Nanchang, P.R. China .
          Article
          DOI: 10.1089/gtmb.2018.0110
          PubMed ID: 30179527
          SO-VID: 746f168b-4c81-4c7a-8125-9817ae0e033d
          History

          Keywords: single nucleotide polymorphism,age-related macular degeneration,complement system,meta-analysis
          Data availability:
          Keywords: single nucleotide polymorphism, age-related macular degeneration, complement system, meta-analysis

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