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      The burden of disease in Spain: results from the global burden of disease study 2010

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          Abstract

          Background

          We herein evaluate the Spanish population’s trends in health burden by comparing results of two Global Burden of Diseases, Injuries, and Risk Factors Studies (the GBD studies) performed 20 years apart.

          Methods

          Data is part of the GBD study for 1990 and 2010. We present results for mortality, years of life lost (YLLs), years lived with disability, and disability-adjusted life years (DALYs) for the Spanish population. Uncertainty intervals for all measures have been estimated.

          Results

          Non-communicable diseases accounted for 3,703,400 (95% CI 3,648,270–3,766,720) (91.3%) of 4,057,400 total deaths, in the Spanish population. Cardiovascular and circulatory diseases were the main cause of mortality among non-communicable diseases (34.7% of total deaths), followed by neoplasms (27.1% of total deaths). Neoplasms, cardiovascular and circulatory diseases, and chronic respiratory diseases were the top three leading causes for YLLs. The most important causes of DALYs in 2010 were neoplasms, cardiovascular and circulatory diseases, musculoskeletal disorders, and mental and behavioral disorders.

          Conclusions

          Mortality and disability in Spain have become even more linked to non-communicable diseases over the last years, following the worldwide trends. Cardiovascular and circulatory diseases, neoplasms, mental and behavioral disorders, and neurological disorders are the leading causes of mortality and disability. Specific focus is needed from health care providers and policy makers to develop health promotion and health education programs directed towards non-communicable disorders.

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          Most cited references19

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          GBD 2010: design, definitions, and metrics.

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            A review of psychological risk factors in back and neck pain.

            S J Linton (2000)
            The literature on psychological factors in neck and back pain was systematically searched and reviewed. To summarize current knowledge concerning the role of psychological variables in the etiology and development of neck and back pain. Recent conceptions of spinal pain, especially chronic back pain, have highlighted the role of psychological factors. Numerous studies subsequently have examined the effects of various psychological factors in neck and back pain. There is a need to review this material to ascertain what conclusions may be drawn. Medical and psychological databases and cross-referencing were used to locate 913 potentially relevant articles. A table of 37 studies was constructed, consisting only of studies with prospective designs to ensure quality. Each study was reviewed for the population studied, the psychological predictor variables, and the outcome. The available literature indicated a clear link between psychological variables and neck and back pain. The prospective studies indicated that psychological variables were related to the onset of pain, and to acute, subacute, and chronic pain. Stress, distress, or anxiety as well as mood and emotions, cognitive functioning, and pain behavior all were found to be significant factors. Personality factors produced mixed results. Although the level of evidence was low, abuse also was found to be a potentially significant factor. Psychological factors play a significant role not only in chronic pain, but also in the etiology of acute pain, particularly in the transition to chronic problems. Specific types of psychological variables emerge and may be important in distinct developmental time frames, also implying that assessment and intervention need to reflect these variables. Still, psychological factors account for only a portion of the variance, thereby highlighting the multidimensional view. Because the methodologic quality of the studies varied considerably, future research should focus on improving quality and addressing new questions such as the mechanism, the developmental time factor, and the relevance that these risk factors have for intervention.
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              The global burden of occupationally related low back pain: estimates from the Global Burden of Disease 2010 study.

              The study was part of the Global Burden of Disease 2010 study and aimed to quantify the burden arising from low back pain (LBP) due to occupational exposure to ergonomic risk factors. Exposure prevalence was based on occupation distribution; estimates of relative risk came from a meta-analysis of relevant published literature. The work-related burden was estimated as disability-adjusted life years (DALYs). Estimates were made for each of 21 world regions and 187 countries, separately for 1990 and 2010 using consistent methods. Worldwide, LBP arising from ergonomic exposures at work was estimated to cause 21.7 million DALYs in 2010. The overall population attributable fraction was 26%, varying considerably with age, sex and region. 62% of LBP DALYs were in males-the largest numbers were in persons aged 35-55 years. The highest relative risk (3.7) was in the agricultural sector. The largest number of DALYs occurred in East Asia and South Asia, but on a per capita basis the biggest burden was in Oceania. There was a 22% increase in overall LBP DALYs arising from occupational exposures between 1990 and 2010 due to population growth; rates dropped by 14% over the same period. LBP arising from ergonomic exposures at work is an important cause of disability. There is a need for improved information on exposure distributions and relative risks, particularly in developing countries.
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                Author and article information

                Contributors
                jmharo@pssjd.org
                s.tyrovolas@pssjd.org
                noe.garin@pssjd.org
                cesardiaztorne@gmail.com
                loreto.carmona@inmusc.eu
                37416lsr@comb.cat
                fperezruiz@telefonica.net
                cjlm@uw.ed
                Journal
                BMC Med
                BMC Med
                BMC Medicine
                BioMed Central (London )
                1741-7015
                5 December 2014
                5 December 2014
                2014
                : 12
                : 1
                : 2
                Affiliations
                [ ]Parc Sanitari Sant Joan de Déu, Universitat de Barcelona, Fundació Sant Joan de Déu. Dr Antoni Pujades, 42, 08830 Sant Boi de Llobregat, Barcelona, Spain
                [ ]Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Salud Mental CIBERSAM, Dr. Esquerdo 46, 28007 Madrid, Spain
                [ ]Unitat de Reumatologia. Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Carrer de Sant Quintí, 89, 08026 Barcelona, Spain
                [ ]Instituto de Salud Musculoesquelética (InMusc), Calle Hilarión, Eslava 2, 28015, Madrid Spain
                [ ]Institute of Bone and Joint Research, Royal North Shore Hospital, University of Sydney, Pacific Hwy, St Leonards, New South Wales 2065 Australia
                [ ]Institut d’Investigació Biomèdica de Bellvitge, Hospital Universitari de Bellvitge, Freixa Llarga s/n, 08907 L’Hospitalet de Llobregat, Barcelona, Spain
                [ ]Rheumatology Division, Cruces University Hospital, Crystal-induced arthritis investigation team, BioCruces Health Investigation Institute, Plaza de Cruces 12, 48903 Baracaldo, Vizcaya Spain
                [ ]Institute for Health Metrics and Evaluation, University of Washington, 2301 Fifth Avenue,mSuite 600, Seattle, WA 98121 USA
                Article
                236
                10.1186/s12916-014-0236-9
                4276068
                7629e036-0dac-4970-b002-ebfbaee3714b
                © Haro et al.; licensee BioMed Central Ltd. 2014

                This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

                History
                : 2 July 2014
                : 12 November 2014
                Categories
                Research Article
                Custom metadata
                © The Author(s) 2014

                Medicine
                disability-adjusted life years,global burden of diseases, injuries, and risk factors studies,spain,mortality,years lived with disability,years of life lost

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