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Ethanol lock and risk of hemodialysis catheter infection in critically ill patients. A randomized controlled trial.
Bertrand Souweine
1 ,
Alexandre Lautrette ,
Didier Gruson ,
Emmanuel Canet ,
Kada Klouche ,
Laurent Argaud ,
Julien Bohe ,
Maïté Garrouste-Orgeas ,
Christophe Mariat ,
François Vincent ,
Sophie Cayot ,
Olivier Cointault ,
Alain Lepape ,
Dominique Guelon ,
Michael Darmon ,
Aurélien Vesin ,
Nicolas Caillot ,
Carole Schwebel ,
Alexandre Boyer ,
Elie Azoulay ,
Lila Bouadma ,
Jean-François Timsit
May 1 2015
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Abstract
Ethanol rapidly eradicated experimental biofilm. Clinical studies of ethanol lock to prevent catheter-related infections (CRIs) suggest preventive efficacy. No such studies have been done in intensive care units (ICU).