Microsatellite Instability as a Prognostic Factor in Stage II Colon Cancer Patients, a Meta-Analysis of Published Literature.

Gkekas, Ioannis; Novotný, Jan; Pecen, Ladislav; Strigård, Karin; Palmqvist, Richard; Gunnarsson, Ulf

doi:10.21873/anticanres.12113

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Microsatellite Instability as a Prognostic Factor in Stage II Colon Cancer Patients, a Meta-Analysis of Published Literature.

Author(s): Ioannis Gkekas ¹ ^, ² , Jan Novotny ² , Ladislav Pecen ³ , Karin Strigård ⁴ , Richard Palmqvist ⁵ , Ulf Gunnarsson ⁴

Publication date (Electronic): December 2017

Journal: Anticancer research

Publisher: International Institute of Anticancer Research

Keywords: Colon cancer, meta-analysis, microsatellite instability, predictive factor, prognostic factor, systematic review

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Abstract

The prognostic role of microsatellite instability (MSI) in stage II colon cancer patients remains controversial despite the fact that it has been investigated in a number of studies. Hazard ratios differ considerably among these studies. We performed a meta-analysis to define the significance of MSI in this group of patients.

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Journal ID (iso-abbrev): Anticancer Res.

Title: Anticancer research

Publisher: International Institute of Anticancer Research

ISSN (Electronic): 1791-7530

ISSN (Print): 0250-7005

Publication date (Electronic): December 2017

Volume: 37

Issue: 12

Affiliations

[1 ] Department of Surgical and Perioperative Sciences, Umea University, Umea, Sweden ioannis.gkekas@nll.se.

[2 ] Department of Surgery, Sunderby hospital Lulea, Lulea, Sweden.

[3 ] Faculty Hospital Pilsen, Charles University, Prague, Czech Republic.

[4 ] Department of Surgical and Perioperative Sciences, Umea University, Umea, Sweden.

[5 ] Department of Medical Biosciences/Pathology, Umea University, Umea, Sweden.

Article

Publisher Item ID: 37/12/6563

DOI: 10.21873/anticanres.12113

PubMed ID: 29187431

SO-VID: 78fe0a9d-d97e-4592-b09a-795f2725ff96

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Keywords: meta-analysis,microsatellite instability,predictive factor,prognostic factor,systematic review,Colon cancer

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Keywords: meta-analysis, microsatellite instability, predictive factor, prognostic factor, systematic review, Colon cancer

Microsatellite Instability as a Prognostic Factor in Stage II Colon Cancer Patients, a Meta-Analysis of Published Literature.

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