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      Comparison of select analytes in aerosol from e-cigarettes with smoke from conventional cigarettes and with ambient air.

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          Abstract

          Leading commercial electronic cigarettes were tested to determine bulk composition. The e-cigarettes and conventional cigarettes were evaluated using machine-puffing to compare nicotine delivery and relative yields of chemical constituents. The e-liquids tested were found to contain humectants, glycerin and/or propylene glycol, (⩾75% content); water (<20%); nicotine (approximately 2%); and flavor (<10%). The aerosol collected mass (ACM) of the e-cigarette samples was similar in composition to the e-liquids. Aerosol nicotine for the e-cigarette samples was 85% lower than nicotine yield for the conventional cigarettes. Analysis of the smoke from conventional cigarettes showed that the mainstream cigarette smoke delivered approximately 1500times more harmful and potentially harmful constituents (HPHCs) tested when compared to e-cigarette aerosol or to puffing room air. The deliveries of HPHCs tested for these e-cigarette products were similar to the study air blanks rather than to deliveries from conventional cigarettes; no significant contribution of cigarette smoke HPHCs from any of the compound classes tested was found for the e-cigarettes. Thus, the results of this study support previous researchers' discussion of e-cigarette products' potential for reduced exposure compared to cigarette smoke.

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          Author and article information

          Journal
          Regul. Toxicol. Pharmacol.
          Regulatory toxicology and pharmacology : RTP
          1096-0295
          0273-2300
          Dec 2014
          : 70
          : 3
          Affiliations
          [1 ] Lorillard Tobacco Company, PO Box 21688, Greensboro, NC, USA. Electronic address: rtayyarah@lortobco.com.
          [2 ] Lorillard Tobacco Company, PO Box 21688, Greensboro, NC, USA.
          Article
          S0273-2300(14)00250-5
          10.1016/j.yrtph.2014.10.010
          25444997
          Copyright © 2014 The Authors. Published by Elsevier Inc. All rights reserved.

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