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      Shear-Wave Elastography for the Diagnosis of Pediatric Hashimoto’s Thyroiditis: A Systematic Review and Meta-Analysis

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          Abstract

          Shear-wave elastography (SWE) has emerged as a novel ultrasonographic technique for the diagnosis of pediatric Hashimoto’s Thyroiditis (HT). This systematic review and meta-analysis aim to summarize current evidence to determine the diagnostic value of SWE for HT. MEDLINE, a comprehensive search yielded five studies inclusive of 392 subjects. A meta-analysis comparing SWE values (kPa) between children with HT and healthy controls yielded a Cohen’s d-value of 1.34 (CI 1.02-1.65), suggesting statistically significant differences in SWE values. Such evidence indicates that SWE may serve as a valuable tool in diagnosing HT in the pediatric population.

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          The PRISMA 2020 statement: an updated guideline for reporting systematic reviews

          Matthew J L Page, Joanne E McKenzie, Patrick Bossuyt … (2024)
          The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement, published in 2009, was designed to help systematic reviewers transparently report why the review was done, what the authors did, and what they found. Over the past decade, advances in systematic review methodology and terminology have necessitated an update to the guideline. The PRISMA 2020 statement replaces the 2009 statement and includes new reporting guidance that reflects advances in methods to identify, select, appraise, and synthesise studies. The structure and presentation of the items have been modified to facilitate implementation. In this article, we present the PRISMA 2020 27-item checklist, an expanded checklist that details reporting recommendations for each item, the PRISMA 2020 abstract checklist, and the revised flow diagrams for original and updated reviews.
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            Summarizing systematic reviews: methodological development, conduct and reporting of an umbrella review approach.

            Edoardo Aromataris, Ritin Fernandez, Christina M Godfrey … (2015)
            With the increase in the number of systematic reviews available, a logical next step to provide decision makers in healthcare with the evidence they require has been the conduct of reviews of existing systematic reviews. Syntheses of existing systematic reviews are referred to by many different names, one of which is an umbrella review. An umbrella review allows the findings of reviews relevant to a review question to be compared and contrasted. An umbrella review's most characteristic feature is that this type of evidence synthesis only considers for inclusion the highest level of evidence, namely other systematic reviews and meta-analyses. A methodology working group was formed by the Joanna Briggs Institute to develop methodological guidance for the conduct of an umbrella review, including diverse types of evidence, both quantitative and qualitative. The aim of this study is to describe the development and guidance for the conduct of an umbrella review.
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              Introduction, comparison, and validation of Meta‐Essentials : A free and simple tool for meta‐analysis

              Robert Suurmond, Henk van Rhee, Tony Hak (2017)
              We present a new tool for meta‐analysis, Meta‐Essentials, which is free of charge and easy to use. In this paper, we introduce the tool and compare its features to other tools for meta‐analysis. We also provide detailed information on the validation of the tool. Although free of charge and simple, Meta‐Essentials automatically calculates effect sizes from a wide range of statistics and can be used for a wide range of meta‐analysis applications, including subgroup analysis, moderator analysis, and publication bias analyses. The confidence interval of the overall effect is automatically based on the Knapp‐Hartung adjustment of the DerSimonian‐Laird estimator. However, more advanced meta‐analysis methods such as meta‐analytical structural equation modelling and meta‐regression with multiple covariates are not available. In summary, Meta‐Essentials may prove a valuable resource for meta‐analysts, including researchers, teachers, and students.
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                Author and article information

                Journal
                Journal ID (nlm-ta): Cureus
                Journal ID (iso-abbrev): Cureus
                Journal ID (issn): 2168-8184
                Title: Cureus
                Publisher: Cureus (Palo Alto (CA) )
                ISSN (Electronic): 2168-8184
                Publication date (Electronic, pub): 26 February 2023
                Publication date (Electronic, collection): February 2023
                Volume: 15
                Issue: 2
                Electronic Location Identifier: e35490
                Affiliations
                [1 ] Radiology, Alabama College of Osteopathic Medicine, Dothan, USA
                [2 ] Medicine, Alabama College of Osteopathic Medicine, Dothan, USA
                [3 ] Orthopaedic Surgery, Alabama College of Osteopathic Medicine, Dothan, USA
                [4 ] Radiology, Decatur Morgan Hospital, Decatur, USA
                Author notes
                Article
                DOI: 10.7759/cureus.35490
                PMC ID: 10049949
                PubMed ID: 37007310
                SO-VID: 79a1a24a-afd9-4ada-8ab2-f700ed0e7a0d
                Copyright © Copyright © 2023, Decker et al.
                License:

                This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

                History
                Date received : 5 February 2023
                Date accepted : 26 February 2023
                Categories
                Subject: Endocrinology/Diabetes/Metabolism
                Subject: Pediatrics
                Subject: Radiology

                Keywords: diagnostic elastography,elastography,shear-wave ultrasonography,shear-wave elastography,pediatrics,hashimoto’s thyroiditis,diagnostic radiology,autoimmune thyroiditis
                Data availability:
                Keywords: diagnostic elastography, elastography, shear-wave ultrasonography, shear-wave elastography, pediatrics, hashimoto’s thyroiditis, diagnostic radiology, autoimmune thyroiditis

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