This review summarizes recent evidence on caregiver burden in mental illness. It examines how the field has advanced in terms of measurement, results, and interventions in 2004/2005, and identifies potential for further studies. Burden has been studied in a much wider spectrum of diagnostic groups and types of caregivers, some brief and practical assessment tools have become available, cultural aspects of burden are better understood, and a high potential for caregiver appraisal to prevent negative consequences of burden has been identified. Recent findings afford a more comprehensive understanding of the caregiving situation and its outcomes, and may find a practical application in devising effective support strategies for family carers, which still seem to be lacking. Substantial progress has been made in the measurement of caregiver burden. In terms of publication quantity, the field is growing rapidly, and international interest in the area is increasing. Improvements in methodological quality are also evident. These new research developments may be taken to reflect an increasing recognition of the contribution of families-away from stigma, shame, and blame. This requires accepting relatives as caregiving experts and as genuine partners in both psychiatric practice and research.