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      Towards a New Era: Is Coronary Artery Disease Reversible?

      research-article
      Author(s):
      Publication date (Electronic):
      Journal: Cardiology
      Publisher: S. Karger AG
      Keywords: Atherosclerosis, Cholesterol, Lipid-lowering trials, Regression

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          Abstract

          There is increasing evidence that conventional lipid-lowering therapy can arrest the progression of coronary atherosclerosis. Trials are now under way to determine whether more radical reduction of low-density-lipoprotein cholesterol will reverse atherosclerosis and lead to regression of coronary lesions. The ability to effect such reductions has been markedly enhanced by the introduction into clinical practice of the 3-hydroxy-3-methylglutaryl coen-zyme A reductase inhibitors.

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          Author and article information

          Journal
          Journal ID (publisher-id): CRD
          Journal ID (nlm-ta): Cardiology
          Journal ID (doi): 10.1159/issn.0008-6312
          Title: Cardiology
          Publisher: S. Karger AG
          ISBN: 978-3-8055-5278-3
          ISBN: 978-3-318-00092-4
          ISSN (Print): 0008-6312
          ISSN (Electronic): 1421-9751
          Publication date Subscription-year: 1990
          Publication date (Print): 1990
          Publication date (Electronic): 12 November 2008
          Volume: 77
          Issue: Suppl 4
          Pages: 66-69
          Affiliations
          MRC Lipoprotein Team, Hammersmith Hospital, London, UK
          Article
          Publisher ID: 174685 Other ID: Cardiology 1990;77:66–69
          DOI: 10.1159/000174685
          PubMed ID: 2073674
          SO-VID: 7f9a6179-cbde-4594-b877-a347970a250b
          Copyright © © 1990 S. Karger AG, Basel
          License:

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          Page count
          Pages: 4
          Categories
          Subject: HMG CoA Reductase Inhibitors: New Horizons in the Management of Hypercholesterolemia

          ScienceOpen disciplines: General medicine,Neurology,Cardiovascular Medicine,Internal medicine,Nephrology
          Keywords: Lipid-lowering trials,Regression,Atherosclerosis,Cholesterol
          Data availability:
          ScienceOpen disciplines: General medicine, Neurology, Cardiovascular Medicine, Internal medicine, Nephrology
          Keywords: Lipid-lowering trials, Regression, Atherosclerosis, Cholesterol

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