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      Effectiveness of the systemic immune inflammation index to predict atrial fibrillation recurrence after cryoablation.

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          Abstract

          Background: We aimed to investigate the predictive role of systemic immune inflammation index (SII) on atrial fibrillation (AF) recurrence following cryoballoon-based AF ablation. Materials & methods: A total of 370 consecutive patients with symptomatic AF who underwent cryoablation were enrolled. The patients were divided into two groups according to recurrence development. Results: During the follow-up period of 25.0 ± 6.7 months, recurrence was observed in 77 patients (20.8%). Receiver operating characteristic analysis demonstrated that using a cutoff level of 532, SII had a sensitivity of 71% and specificity of 68%. In the multivariate Cox model, high SII was a significant predictor of the recurrence. Conclusion: This study showed that higher SII level is an independent predictor of AF recurrence.

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          Author and article information

          Journal
          Biomark Med
          Biomarkers in medicine
          Informa UK Limited
          1752-0371
          1752-0363
          Jan 2023
          : 17
          : 2
          Affiliations
          [1 ] Department of Cardiology, University of Health Sciences, Ankara City Hospital, Ankara, 06800, Turkey.
          [2 ] Department of Cardiology, Medipol University, Bahçelievler Medipol Hospital, İstanbul, 34196, Turkey.
          Article
          10.2217/bmm-2022-0515
          37042445
          83670bc1-7a39-42ba-bc61-6d680645daa8
          History

          biomarker,cryoballoon ablation,inflammation,systemic immune inflammation index,recurrence,atrial fibrillation

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