In contrast to ordinary symmetries, supersymmetry interchanges bosons and fermions. Originally proposed as a symmetry of our universe, it still awaits experimental verification. Here we theoretically show that supersymmetry emerges naturally in topological superconductors, which are well-known condensed matter systems. Specifically, we argue that the quantum phase transitions at the boundary of topological superconductors in both two and three dimensions display supersymmetry when probed at long distances and times. Supersymmetry entails several experimental consequences for these systems, such as, exact relations between quantities measured in disparate experiments, and in some cases, exact knowledge of the universal critical exponents. The topological surface states themselves may be interpreted as arising from spontaneously broken supersymmetry, indicating a deep relation between topological phases and SUSY. We discuss prospects for experimental realization in films of superfluid He\(_3\)-B.