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      High cut-off dialysis in chronic haemodialysis patients.

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          Abstract

          Haemodialysis patients suffer from chronic systemic inflammation and high incidence of cardiovascular disease. One cause for this may be the failure of diseased kidneys to eliminate immune mediators. Current haemodialysis treatment achieves insufficient elimination of proteins in the molecular weight range 15-45 kD. Thus, high cut-off dialysis might improve the inflammatory state.

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          Author and article information

          Journal
          Eur. J. Clin. Invest.
          European journal of clinical investigation
          Wiley-Blackwell
          1365-2362
          0014-2972
          Dec 2015
          : 45
          : 12
          Affiliations
          [1 ] Department of Internal Medicine II, Martin-Luther-University Halle, Halle, Germany.
          [2 ] Institute for Clinical Epidemiology and Applied Biometry, University of Tübingen, Tübingen, Germany.
          [3 ] NMI Technology Transfer GmbH, Reutlingen, Germany.
          [4 ] Department of Research and Development, Gambro Dialysatoren GmbH, Hechingen, Germany.
          [5 ] Institute for Chemistry, Food Chemistry, Martin-Luther-University Halle, Halle, Germany.
          [6 ] Department of Nephrology and Internal Intensive Care Medicine, Charité-Universitaetsmedizin Berlin, Campus Virchow Clinic, Berlin, Germany.
          Article
          10.1111/eci.12559
          26519693
          8509bb6b-3c05-422a-870b-2387a95051d4
          History

          High cut-off membrane,haemodialysis,inflammation,monocytes,multiplex immunoassay

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