7
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Evidencia serológica de infección por hantavirus (Bunyaviridae: Hantavirus) en roedores del Departamento de Sucre, Colombia Translated title: Serological evidence of hanta virus infection (Bunyaviridae: Hantavirus) in rodents from the Sucre Department in Colombia

      research-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Objetivo Determinar la frecuencia de anticuerpos específicos a hantavirus en roedores del municipio de San Marcos, departamento de Sucre. Métodos Se capturaron 144 roedores con trampas Sherman® en áreas urbanas y rurales del municipio de San Marcos, desde diciembre de 2007 hasta julio de 2009. Los anticuerpos Ig G específicos contra el Virus Sin Nombre (VSN) fueron detectados en muestras de plasma mediante ELISA indirecto. Resultados La seroprevalencia de anticuerpos contra hantavirus fue del 8,3 % (12/144 capturas). Los porcentajes de seropositividad específicos por especie variaron entre 6,8 % (3/44, Zygodontomys brevicauda) y 50 % (1/2, Neacomys spinosus). No se encontró diferencia estadística en la seroprevalencia con respecto al área de muestreo, sexo y etapa reproductiva (p>0,05); sin embargo, hubo un mayor número de machos adultos seropositivos. Conclusiones Se evidenció por primera vez seropositividad a hantavirus en roedores de la subfamilia Murinae en Colombia. La detección de anticuerpos contra el virus refuerza la hipótesis que sugiere la circulación de al menos un hantavirus en roedores del norte colombiano.

          Translated abstract

          Objective The main goal of this research was to determine the frequency of hantavirus-specific antibodies in rodents from the municipality of San Marcos in the Sucre department of Colombia. Methods 144 rodents were captured in San Marcos' urban and rural areas using Sherman traps between December 2007 and July 2009. "Virus sin Nombre" (SNV)-specific antibodies were detected in plasma samples by an indirect ELISA immunoassay. Results An 8.3 % (12/144) seroprevalence rate was found. Specific seropositivity rates ranged from 6.8 % (3/44, Zygodontomysbrevicauda) to 50 % (1/2, Neacomysspinosus). No significant differences were found in seroprevalence according to capture area, gender and/or reproductive stage (p>0.05); however, there were more seropositive adult males. Conclusion This is the first evidence of hanta virus seropositivity in rodents from the Murinae subfamily in Colombia. The presence of SNV antibodies in rodents in San Marcos supported the hypothesis that at least one hantavirusis circulating in rodents from northern Colombia.

          Related collections

          Most cited references29

          • Record: found
          • Abstract: found
          • Article: not found

          Hantaviruses: a global disease problem.

          Hantaviruses are carried by numerous rodent species throughout the world. In 1993, a previously unknown group of hantaviruses emerged in the United States as the cause of an acute respiratory disease now termed hantavirus pulmonary syndrome (HPS). Before than, hantaviruses were known as the etiologic agents of hemorrhagic fever with renal syndrome, a disease that occurs almost entirely in the Eastern Hemisphere. Since the discovery of the HPS-causing hantaviruses, intense investigation of the ecology and epidemiology of hantaviruses has led to the discovery of many other novel hantaviruses. Their ubiquity and potential for causing severe human illness make these viruses an important public health concern; we reviewed the distribution, ecology, disease potential, and genetic spectrum.
            Bookmark
            • Record: found
            • Abstract: not found
            • Article: not found

            Genetic identification of a hantavirus associated with an outbreak of acute respiratory illness

              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Isolation of Hantaan virus, the etiologic agent of Korean hemorrhagic fever, from wild urban rats.

              Urban rats captured in Seoul and four nearby Korean cities were found to have immunofluorescent antibodies reactive with Hantaan virus, the etiologic agent of Korean hemorrhagic fever (KHF). Serum antibodies were detected in 13% from 477 Rattus norvegicus and 11% of 47 Rattus rattus. Hantaan viral antigen was found in pulmonary tissues of 42 animals, and Hantaan virus was recovered from 23 rats, all but two of which were R. norvegicus. Wistar rats were qualitatively much more sensitive than Apodemus agrarius rodents for isolation of virus from tissues of wild rats. Wistar rats inoculated with one of these strains had virus in lung and spleen for at least 75 days. These results document the existence of an urban cycle for Hantaan virus, which had been suspected on the basis of the occurrence of sporadic urban cases in humans of KHF, and suggest that Rattus-borne Hantaan virus may be widely distributed in urban centers.
                Bookmark

                Author and article information

                Journal
                rsap
                Revista de Salud Pública
                Rev. salud pública
                Instituto de Salud Publica, Facultad de Medicina - Universidad Nacional de Colombia (Bogotá, DF, Colombia )
                0124-0064
                September 2012
                : 14
                : 5
                : 755-764
                Affiliations
                [01] orgnameUniversidad de Sucre orgdiv1Grupo Investigaciones Biomédicas
                Article
                S0124-00642012000500003 S0124-0064(12)01400503
                8568a039-8722-49f6-8d43-faf49a59f3ad

                This work is licensed under a Creative Commons Attribution 4.0 International License.

                History
                : 2012
                : 07 October 2012
                : 01 June 2011
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 33, Pages: 10
                Product

                SciELO Colombia

                Self URI: Texto completo solamente en formato PDF (ES)
                Categories
                Artículos/Investigación

                rodentia,Colombia,Hantavirus,seroprevalencia,roedores,seroprevalence

                Comments

                Comment on this article