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Abstract

Some aspects of the roles of inositol trisphosphate (Insp3) and inositol tetrakisphosphate (Insp4) in Ca2+ homeostasis in terms of inositol trisphosphate 3-kinase B (IP3K-B) localization and activity are discussed. The model that we propose is also compatible with IP3K-B participating in the widely reported phenomenon of quantal release of Ca2+ from internal stores, at least in some biological systems.

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PubMed ID:: 9038348

DOI:: 10.1016/S0014-5793(96)01516-5

ScienceOpen disciplines: Chemistry

Keywords: Animals,Calcium,metabolism,Calcium Channels,Cell Membrane,Enzyme Activation,Fluorescent Antibody Technique,Homeostasis,physiology,Inositol 1,4,5-Trisphosphate,Inositol 1,4,5-Trisphosphate Receptors,Inositol Phosphates,Models, Biological,Phosphotransferases (Alcohol Group Acceptor),Rats,Receptors, Cytoplasmic and Nuclear,Signal Transduction

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ScienceOpen disciplines: Chemistry

Keywords: Animals, Calcium, metabolism, Calcium Channels, Cell Membrane, Enzyme Activation, Fluorescent Antibody Technique, Homeostasis, physiology, Inositol 1,4,5-Trisphosphate, Inositol 1,4,5-Trisphosphate Receptors, Inositol Phosphates, Models, Biological, Phosphotransferases (Alcohol Group Acceptor), Rats, Receptors, Cytoplasmic and Nuclear, Signal Transduction

Possible roles of inositol 1,4,5-trisphosphate 3-kinase B in calcium homeostasis.

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