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      The Expression of Water Channels AQP1 and AQP2 in a Large Series of ADPKD Kidneys

      Nephron

      S. Karger AG

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          Abstract

          We read with interest the paper by Hayashi et al. [1] reporting the expression of AQP2 and AQP3 in cyst-lining epithelial cells from ADPKD kidneys. The authors suggest that about 30% of the cysts in ADPKD are derived from collecting-duct cells and that these cells remain well differentiated in terms of AQP expression. However, these conclusions are limited by the small number of ADPKD kidneys (n = 2) studied and by the fact that both AQP2 and AQP3 are located in the same cells – the principal cells of the collecting duct.

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          Author and article information

          Journal
          NEF
          Nephron
          10.1159/issn.1660-8151
          Nephron
          S. Karger AG
          1660-8151
          2235-3186
          1998
          January 1998
          19 December 1997
          : 78
          : 1
          : 116
          Affiliations
          Division of Nephrology, St. Luc Academic Hospital, University of Louvain Medical School, Brussels, Belgium
          Article
          44893 Nephron 1998;78:116
          10.1159/000044893
          9453414
          © 1998 S. Karger AG, Basel

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          Page count
          References: 3, Pages: 1
          Product
          Self URI (application/pdf): https://www.karger.com/Article/Pdf/44893
          Categories
          Letter to the Editor

          Cardiovascular Medicine, Nephrology

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