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      Shading correction for volumetric CT using deep convolutional neural network and adaptive filter

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          Abstract

          Background

          Shading artifact may lead to CT number inaccuracy, image contrast loss and spatial non-uniformity (SNU), which is considered as one of the fundamental limitations for volumetric CT (VCT) application. To correct the shading artifact, a novel approach is proposed using deep learning and an adaptive filter (AF).

          Methods

          Firstly, we apply the deep convolutional neural network (DCNN) to train a human tissue segmentation model. The trained model is implemented to segment the tissue. According to the general knowledge that CT number of the same human tissue is approximately the same, a template image without shading artifact can be generated using segmentation and then each tissue is filled with the corresponding CT number of a specific tissue. By subtracting the template image from the uncorrected image, the residual image with image detail and shading artifact are generated. The shading artifact is mainly low-frequency signals while the image details are mainly high-frequency signals. Therefore, we proposed an adaptive filter to separate the shading artifact and image details accurately. Finally, the estimated shading artifacts are deleted from the raw image to generate the corrected image.

          Results

          On the Catphan©504 study, the error of CT number in the corrected image’s region of interest (ROI) is reduced from 109 to 11 HU, and the image contrast is increased by a factor of 1.46 on average. On the patient pelvis study, the error of CT number in selected ROI is reduced from 198 to 10 HU. The SNU calculated from the ROIs decreases from 24% to 9% after correction.

          Conclusions

          The proposed shading correction method using DCNN and AF may find a useful application in future clinical practice.

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          Author and article information

          Journal
          Quant Imaging Med Surg
          Quant Imaging Med Surg
          QIMS
          Quantitative Imaging in Medicine and Surgery
          AME Publishing Company
          2223-4292
          2223-4306
          July 2019
          July 2019
          : 9
          : 7
          : 1242-1254
          Affiliations
          [1 ]Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences , Shenzhen 518055, China;
          [2 ]Shenzhen College of Advanced Technology, University of Chinese Academy of Sciences , Shenzhen 518055, China;
          [3 ]Beaumont Health System, Royal Oak, MI, USA;
          [4 ]School of Information Engineering, Guangdong Medical University , Dongguan 523808, China
          Author notes
          Correspondence to: Yaoqin Xie. Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China. Email: yq.xie@ 123456siat.ac.cn ; Huailing Zhang. School of Information Engineering, Guangdong Medical University, Dongguan 523808, China. Email: huailing@ 123456163.com .
          Article
          PMC6685805 PMC6685805 6685805 qims-09-07-1242
          10.21037/qims.2019.05.19
          6685805
          31448210
          8859fcec-db6c-4399-ace1-91c7e97d14af
          2019 Quantitative Imaging in Medicine and Surgery. All rights reserved.
          History
          : 30 March 2019
          : 15 May 2019
          Categories
          Original Article

          volumetric CT (VCT),Shading artifact,deep convolution neural network,adaptive filter (AF)

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